Comparison of Brain MRI Findings between Patients with Alzheimer's Disease and Non-Dementia Psychiatric Disorders in the Elderly

Ji Xinyu, Lian Yong, Guanglai Dong, Xiaoqian Ding, Liu Xin
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Abstract

Objectives: This study aimed to investigate differences in brain structure between Alzheimer's disease (AD) and non-dementia psychiatric disorders (SNDMD) patients using MRI imaging for accurate diagnosis. Methods: A total of 50 AD patients and 50 SNDMD patients underwent head MRI scans, and brain structures were measured and compared using SPSS software. The MRI results were interpreted by two radiologists. Results: AD patients had wider sulci and larger ventricular systems compared to SNDMD patients and normal elderly individuals. SNDMD patients had less cortical atrophy than AD patients. Conclusion: The �ndings suggest that MRI is a useful tool for differentiating AD from SNDMD and aiding in early diagnosis. However, it should be noted that MRI is not a de�nitive diagnostic tool.
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老年痴呆症患者与非老年痴呆症精神障碍患者大脑核磁共振成像结果的比较
研究目的本研究旨在利用磁共振成像技术研究阿尔茨海默病(AD)和非痴呆性精神障碍(SNDMD)患者大脑结构的差异,以进行准确诊断。研究方法对 50 名 AD 患者和 50 名 SNDMD 患者进行头部磁共振成像扫描,并使用 SPSS 软件测量和比较大脑结构。核磁共振成像结果由两名放射科医生解读。结果显示与 SNDMD 患者和正常老年人相比,AD 患者的脑沟更宽,脑室系统更大。SNDMD患者的皮质萎缩程度低于AD患者。结论:研究结果表明,磁共振成像是区分AD和SNDMD的有效工具,有助于早期诊断。但需要注意的是,核磁共振成像并不是一种明确的诊断工具。
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