Human Amylin as a Novel Diagnostic Marker for Hypothyroidism in Iraqi Patients

IF 1.2 Q3 MULTIDISCIPLINARY SCIENCES Baghdad Science Journal Pub Date : 2023-12-24 DOI:10.21123/bsj.2023.8655
Duha Khalil Ibrahim, Layla Othman
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Abstract

Amylin is a peptide hormone that the pancreas cell secretes along with insulin.  As a neuroendocrine hormone that sends a specific signal to the brain, amylin is essential for maintaining homeostasis in the metabolism. The goal of the current study is to determine the role of Amylin as a diagnostic   marker of hypothyroidism.  The 120 samples were divided into two groups (80 patients with hypothyroidism) and the second group (40 healthy people). Amylin levels significantly increased compared to the control group in the group with hypothyroidism, according to the data (p < 0.001). Amylin levels raised in Iraqi patients with Hypothyroidism. Amylin a good diagnostic marker for Hypothyroidism with most accurately, sensitively cut off value 51.
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人淀粉样蛋白作为伊拉克患者甲状腺功能减退症的新型诊断标志物
淀粉样蛋白是胰腺细胞与胰岛素一起分泌的一种肽类激素。 作为一种向大脑发出特定信号的神经内分泌激素,淀粉样蛋白对维持新陈代谢的平衡至关重要。本研究的目的是确定淀粉样蛋白作为甲状腺功能减退症诊断标志物的作用。 120 份样本被分为两组(80 名甲减患者)和第二组(40 名健康人)。数据显示,与对照组相比,甲状腺功能减退症组的淀粉酶水平明显升高(p < 0.001)。伊拉克甲减患者的淀粉样蛋白水平升高。淀粉样蛋白是甲状腺功能减退症的良好诊断指标,其最准确、最灵敏的临界值为51。
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来源期刊
Baghdad Science Journal
Baghdad Science Journal MULTIDISCIPLINARY SCIENCES-
CiteScore
2.00
自引率
50.00%
发文量
102
审稿时长
24 weeks
期刊介绍: The journal publishes academic and applied papers dealing with recent topics and scientific concepts. Papers considered for publication in biology, chemistry, computer sciences, physics, and mathematics. Accepted papers will be freely downloaded by professors, researchers, instructors, students, and interested workers. ( Open Access) Published Papers are registered and indexed in the universal libraries.
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