REALIZATION OF 650 NM FIBER-COUPLED DIODE LASERS MODULE WITH OUTPUT BEAM REDIRECTION FOR APPLICATION IN PHOTOTHERAPY AND PHOTODYNAMIC INACTIVATION OF BACTERIALS

Nguyen Thanh Phuong, Luong Huu Bac, Quan Thi Minh Nguyet, DO Thi Kim Thoa, Nguyen Ngoc Trung, Tong Quang Cong, Tran Quoc Tien
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Abstract

Currently, diode lasers in the red wavelength region, especially at 650 nm, are extensively utilized in phototherapy and photodynamic inactivation of bacterials by numerous research groups in the field of lasers for biomedical application. These devices offer exceptional advantages, such as their compact size, ease of design and integration, user-friendliness, and high safety for both operators and patients. Among these, fiber-coupled diode lasers provide an efficient solution for delivering radiation from the laser chip to the desired location. However, further optimization is still required for the fabrication technological development of these devices to meet specific application needs. This includes aspects like reducing manufacturing costs, improving component usability during operation, and meeting specialized usage requirements. To develop the technology for device fabrication, addressing the aforementioned demands, we conducted research on the design, fabrication, and characterization of fiber-coupled semiconductor lasers operating at a wavelength of 650 nm. The characterization results demonstrate that the manufactured devices can operate at maximal pumping current of 100 mA and under varying temperatures from 25oC to 40oC. Additionally, a radiation output orientation module has been designed and integrated at the end of the optical fiber to meet various demands in phototherapy and photodynamic inactivation of bacterials.
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实现具有输出光束重定向功能的 650 nm 光纤耦合二极管激光器模块在光疗和细菌光动力灭活中的应用
目前,生物医学应用激光领域的许多研究小组都在广泛使用红色波长区域(尤其是 650 纳米波长)的二极管激光器进行光疗和光动力灭活细菌。这些设备具有结构紧凑、易于设计和集成、使用方便以及对操作者和患者都非常安全等独特优势。其中,光纤耦合二极管激光器是将辐射从激光芯片传输到所需位置的高效解决方案。然而,这些设备的制造技术开发仍需进一步优化,以满足特定的应用需求。这包括降低制造成本、提高组件在运行过程中的可用性以及满足特殊使用要求等方面。为了开发设备制造技术,满足上述需求,我们对波长为 650 纳米的光纤耦合半导体激光器的设计、制造和特性进行了研究。表征结果表明,所制造的设备可在最大泵浦电流为 100 mA 和 25oC 至 40oC 的不同温度下工作。此外,还设计并在光纤末端集成了辐射输出定向模块,以满足光疗和光动力灭活细菌的各种需求。
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HỆ THỐNG QUẢN LÝ GIẤY ĐI ĐƯỜNG TRỰC TUYẾN: GIẢI PHÁP ỨNG DỤNG CÔNG NGHỆ SỐ CỦA TRƯỜNG ĐẠI HỌC VINH REALIZATION OF 650 NM FIBER-COUPLED DIODE LASERS MODULE WITH OUTPUT BEAM REDIRECTION FOR APPLICATION IN PHOTOTHERAPY AND PHOTODYNAMIC INACTIVATION OF BACTERIALS REGULAR ACTIVITIES OF ADULT PTYAS MUCOSA (LINNAEUS, 1758) IN A FARMING CONDITIONS OF NGHE AN PROVINCE, VIET NAM CHUYỂN ĐỔI SỐ TRONG QUẢN LÝ HOẠT ĐỘNG ĐÀO TẠO Ở TRƯỜNG ĐẠI HỌC VẤN ĐỀ XÁC LẬP VỊ TRÍ ĐẶC THÙ CỦA NGƯỜI TRÍ THỨC TRONG TIỂU THUYẾT MA VĂN KHÁNG
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