Computed tomography reconstruction and morphometric analysis of the humerus and femur in New Zealand rabbits

M. L. Selcuk
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Abstract

Aim: This study was carried out to create three-dimensional (3D) models of the humerus and femur using computed tomography (CT) images of the New Zealand rabbit and to reveal whether there are differences between sexes and the right and left sides. Materials and Methods: The study was applied on 14 month old (10 male and 10 female) New Zealand rabbits. First, 0.5 mm thick images of the animals were taken by computed tomography (CT) and saved in DICOM format. Then, 3D models of the humerus and femur were obtained by reconstructing the images with the MIMICS 20.1 program. Morphometric data were obtained from the obtained 3D model. After this procedure, the rabbits were dissected and the weights of the humerus and femur were measured. Results: It was determined that the right humerus and femur volume and surface area in male rabbits were larger from the left side (p<0.05). There was no difference between the other morphometric values examined and rabbit bones did not show homotypic variation. In addition, it was thought that the humerus and femur bones could not be used to determine gender because the differences between the sexes were insignificant. Conclusion: It was thought that this study would provide the basis for studies and experimental models on rabbits by revealing the morphological features of the humerus and femur and would help the physician in the diagnosis of diseases by forming the basis of the data obtained with the imaging systems used in the clinical field.
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新西兰兔肱骨和股骨的计算机断层扫描重建和形态计量分析
目的:本研究旨在利用新西兰兔的计算机断层扫描(CT)图像创建肱骨和股骨的三维(3D)模型,并揭示性别和左右侧之间是否存在差异。材料和方法:研究对象为 14 个月大(10 雄 10 雌)的新西兰兔。首先,用计算机断层扫描(CT)拍摄动物 0.5 毫米厚的图像,并保存为 DICOM 格式。然后,用 MIMICS 20.1 程序重建图像,获得肱骨和股骨的三维模型。从获得的三维模型中获取形态测量数据。之后,解剖兔子并测量肱骨和股骨的重量。结果结果表明,雄兔右侧肱骨和股骨的体积和表面积均大于左侧(P<0.05)。其他形态测量值之间没有差异,兔子骨骼也没有同型变异。此外,由于肱骨和股骨的性别差异不明显,因此认为不能用肱骨和股骨来确定性别。结论这项研究通过揭示肱骨和股骨的形态特征,为兔子的研究和实验模型提供了依据,并通过形成临床领域使用的成像系统所获得的数据基础,帮助医生诊断疾病。
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