Tuberculosis pleural y endocarditis como complicaciones de origen multifactorial en granulomatosis con poliangítis. Reporte de caso clínico

IF 1.2 Q4 RHEUMATOLOGY Reumatologia Clinica Pub Date : 2023-12-29 DOI:10.1016/j.reuma.2023.08.002
Jesús Anguamea-Maldonado, Eduardo Sanchez-Zazueta, Rene Vidal-Morales
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Abstract

We present the case of a 36-year-old woman with a history of granulomatosis with polyangiitis, chronic kidney disease, and systemic arterial hypertension. Debut with dyspnea, weakness, and hemoptysis, she was suspected in atypical pneumonia, discarded, persisting with tachypnea, tachycardia, and chest pain. The protocol for pulmonary tuberculosis was started with negative sputum samples, positive blood culture for Staphylococcus haemolyticus, chest tomography with left pneumothorax and ipsilateral pleural effusion, exudate-type pleural fluid was obtained, acid-fast staining, negative PCR for Mycobacterium tuberculosis. A follow-up echocardiogram was performed due to a new murmur, reporting valvular vegetation, concluding a diagnosis of pleural tuberculosis and endocarditis as complications of multifactorial origin associated with immunosuppression in granulomatosis with polyangiitis.

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胸膜结核和心内膜炎是肉芽肿伴多血管炎的多因素并发症。临床病例报告
我们介绍了一例 36 岁女性的病例,她曾患有肉芽肿伴多血管炎、慢性肾病和系统性动脉高血压。因呼吸困难、乏力和咯血而首次就诊,被怀疑为非典型肺炎,后被排除,并持续出现呼吸急促、心动过速和胸痛。痰标本阴性,溶血性葡萄球菌血培养阳性,胸部断层扫描显示左侧气胸和同侧胸腔积液,获得渗出型胸腔积液,酸性染色,结核分枝杆菌 PCR 阴性。由于出现了新的杂音,患者接受了超声心动图复查,结果显示存在瓣膜植被,最终诊断为胸膜结核和心内膜炎,这是肉芽肿伴多血管炎免疫抑制引起的多因素并发症。
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来源期刊
Reumatologia Clinica
Reumatologia Clinica RHEUMATOLOGY-
CiteScore
2.40
自引率
6.70%
发文量
105
审稿时长
54 days
期刊介绍: Una gran revista para cubrir eficazmente las necesidades de conocimientos en una patología de etiología, expresividad clínica y tratamiento tan amplios. Además es La Publicación Oficial de la Sociedad Española de Reumatología y del Colegio Mexicano de Reumatología y está incluida en los más prestigiosos índices de referencia en medicina.
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