DETERMINANTS OF MYOCARDIAL INFARCTION OUTCOMES IN A NON-PERCUTANEOUS CORONARY INTERVENTION HOSPITAL IN JAKARTA

Talitha Syifa Laili, Wiwin Winarti
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Abstract

Background: Global cardiovascular challenges persist, notably in myocardial infarction (MI). Despite studying factors such as age, sex, MI type, and comorbidities impacting survival, knowledge gaps exist, particularly in Indonesia without recent MI data, especially in non-PCI settings. Objectives: This study seeks to bridge the knowledge gap concerning determinants of post-MI survival in hospitals without PCI facilities in Jakarta, Indonesia. Methods: Adopting a retrospective cross-sectional design, 112 medical record patients from an Emergency Department of non-PCI hospital in Jakarta were selected via purposive sampling. A structured checklist was utilized to assess 16 variables and the primary endpoint was post-treatment status. The study employed Chi-square, Fisher's exact, and Likelihood ratio tests to analyze the relationship between demographics, risk Factors, and MI treatment access and the post-treatment status. Results: Results highlighted that of 112 myocardial infarction (MI) patients, males constituted 70.5%, with Non-ST Elevation Myocardial Infarction as the predominant subtype (57.1%). Most participants (86.6%) were ≥45 years old. Prevalence rates included hypertension (56.3%), Diabetes Mellitus (40.2%), Congestive Heart Failure (42.0%), and prior MI (27.7%). Post-MI survival stood at 92.9%, with 7.1% mortality. The results revealed a significant correlation between cardiogenic shock and MI outcomes (p=0.000), indicating a protective advantage (OR: 0.018) for those without cardiogenic shock against MI-related mortality. Conclusion: While cardiogenic shock has been reaffirmed as the sole predictor of post-myocardial infarction mortality in our study, it's crucial to heighten awareness of other MI determinants, including age, gender disparities, smoking status, and the dynamics of therapeutic measures. This underlines the pressing need for early identification and evidence-based management strategies.
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雅加达一家非经皮冠状动脉介入治疗医院心肌梗死预后的决定因素
背景:全球心血管疾病仍面临挑战,尤其是心肌梗死(MI)。尽管对影响存活率的年龄、性别、心肌梗死类型和合并症等因素进行了研究,但仍存在知识差距,特别是在没有近期心肌梗死数据的印度尼西亚,尤其是在非 PCI 环境中。 研究目的本研究旨在填补印尼雅加达没有 PCI 设施的医院中有关心肌梗死后存活率决定因素的知识空白。 研究方法采用回顾性横断面设计,通过目的性抽样从雅加达一家非 PCI 医院的急诊科选取了 112 名有医疗记录的患者。采用结构化核对表评估 16 个变量,主要终点为治疗后状态。研究采用了卡方检验、费雪精确检验和似然比检验来分析人口统计学、风险因素、心肌梗死治疗机会与治疗后状态之间的关系。 结果结果显示,在 112 名心肌梗死(MI)患者中,男性占 70.5%,主要亚型为非 ST 段抬高型心肌梗死(57.1%)。大多数参与者(86.6%)的年龄≥45 岁。发病率包括高血压(56.3%)、糖尿病(40.2%)、充血性心力衰竭(42.0%)和既往心肌梗死(27.7%)。心肌梗死后存活率为 92.9%,死亡率为 7.1%。结果显示,心源性休克与心肌梗死结果之间存在明显的相关性(P=0.000),表明无心源性休克者对心肌梗死相关死亡率具有保护性优势(OR:0.018)。 结论:在我们的研究中,心源性休克再次被确认为心肌梗死后死亡率的唯一预测因素,但我们也必须提高对其他心肌梗死决定因素的认识,包括年龄、性别差异、吸烟状况和治疗措施的动态变化。这强调了早期识别和循证管理策略的迫切需要。
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