The use of gut microbiota probiotics in the management of atopic dermatitis in children: systematic review

D. P. K. Wedayanti
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Abstract

Atopic dermatitis (AD) is one of the most common inflammatory skin diseases, affecting more than 20% of the population at some time in their lives. Currently, corticosteroids are generally used for the treatment of AD, although these drugs have the potential to cause more serious side effects. Objective of the study was to find out the role of probiotics in the management of atopic dermatitis in children through a review of previous research. A PubMed search was carried out with the keywords 'atopic dermatitis' and 'probiotic' from databases for the last 10 years (2014-2023). Researchers present the results in narrative form and in table form. A total of 10 articles were included in this study. The research comes from several different countries with the research time being from 2017 to 2022. Each study describes the author, year of study, total sample, type of probiotic, duration of treatment, results and side effects. Giving probiotics to pediatric patients with atopic dermatitis has an impact on reducing SCORAD in evaluation after 2-3 months (8-12 weeks). No significant side effects were found in the included studies.
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使用肠道微生物益生菌治疗儿童特应性皮炎:系统综述
特应性皮炎(AD)是最常见的炎症性皮肤病之一,20%以上的人在一生中都会受到影响。目前,治疗特应性皮炎一般使用皮质类固醇激素,但这类药物有可能导致更严重的副作用。本研究旨在通过回顾以往的研究,了解益生菌在治疗儿童特应性皮炎中的作用。研究人员以 "特应性皮炎 "和 "益生菌 "为关键词,在PubMed数据库中对过去10年(2014-2023年)的研究进行了检索。研究人员以叙述和表格的形式呈现研究结果。本研究共收录了 10 篇文章。这些研究来自多个不同的国家,研究时间为 2017 年至 2022 年。每项研究都介绍了作者、研究年份、样本总数、益生菌类型、治疗持续时间、结果和副作用。在2-3个月(8-12周)后的评估中,给患有特应性皮炎的儿童患者服用益生菌对降低SCORAD有影响。所纳入的研究未发现明显的副作用。
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