DYNAMICS AND CONTROL OF BRUCELLOSIS IN HUMAN AND LIVESTOCK: PUBLIC HEALTH EDUCATION, TREATMENT AND VACCINATION

M. B. Abdullahi, Amiru Sule
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Abstract

Brucellosis is a multifaceted zoonotic infection with vital epidemiological, economic, and global health effect, principally for human and Livestock populations within developing nations. In this paper a dynamic model of livestock-to-human transmission of the disease is developed. Model investigation is carried out to obtain and establish the stability of the equilibrium points. The basic reproduction number is calculated and the conditions under which brucellosis can be cleared in the both populations are established. Then, optimal control approach to establish the required conditions for the optimality of the disease eradication or control are applied. Public health education for humans and vaccination for susceptible livestock and treatment for infected humans and livestock. Numerical simulations show the dynamics of disease transmission and the effect of the control strategies.
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人类和牲畜布鲁氏菌病的动态和控制:公共卫生教育、治疗和疫苗接种
布鲁氏菌病是一种多方面的人畜共患传染病,对流行病学、经济和全球健康都有重要影响,主要是对发展中国家的人类和牲畜群体。本文建立了该疾病从牲畜到人类传播的动态模型。对模型进行了研究,以获得并确定平衡点的稳定性。计算了基本繁殖数量,并确定了布鲁氏菌病可在两个种群中清除的条件。然后,应用最优控制方法来确定消除或控制疾病的最优化所需的条件。对人类进行公共卫生教育,对易感牲畜进行疫苗接种,对受感染的人类和牲畜进行治疗。数值模拟显示了疾病传播的动态和控制策略的效果。
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