Exploring Indigenous Medicinal Plants for Managing Diabetes Mellitus in Uganda: Ethnobotanical Insights, Pharmacotherapeutic Strategies, and National Development Alignment

U. Paul-Chima, Kungu Erisa, Inyangat Raphael, O. Emmanuel I., A. Ugo, Okon Michael B.,, Shanthi Subbarayan, Vidya Sankarapandiyan
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Abstract

Diabetes Mellitus (DM) stands as a pressing global health concern, particularly in Uganda, where its prevalence mirrors global trends driven by urbanization, lifestyle changes, and genetic predispositions. This study delves into Uganda's rich heritage of medicinal plants, investigating their use in managing DM within local communities. A comprehensive review was conducted, exploring the epidemiology and pathophysiology of DM in Uganda, emphasizing genetic predispositions, lifestyle factors, and the healthcare landscape. The study unveils indigenous medicinal plants employed for DM management, detailing their usage, preparation, and potential therapeutic properties. Additionally, the pharmacotherapeutic landscape for DM management, encompassing oral hypoglycemic agents, injectable therapies, and adjunctive medications, is scrutinized in alignment with Uganda's healthcare policies. Moreover, the study aligns strategies for DM management with Uganda's National Development Plan (NDP), outlining an integrative approach for healthcare infrastructure, primary care strengthening, sustainable financing, health information systems, and collaborative partnerships. Keywords: Diabetes Mellitus, Medicinal Plants, Uganda, Ethnobotany, Pharmacological Evaluation, National Development Plan, Integrated Healthcare Strategies
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探索乌干达治疗糖尿病的本土药用植物:人种植物学见解、药物治疗策略和国家发展协调
糖尿病(DM)是全球亟待解决的健康问题,尤其是在乌干达,其发病率反映了城市化、生活方式改变和遗传倾向所导致的全球趋势。本研究深入探讨了乌干达丰富的药用植物遗产,调查了它们在当地社区管理糖尿病中的应用。研究对乌干达 DM 的流行病学和病理生理学进行了全面回顾,强调了遗传倾向、生活方式因素和医疗保健环境。研究揭示了当地用于 DM 治疗的药用植物,详细介绍了其用法、制备方法和潜在的治疗特性。此外,研究还结合乌干达的医疗保健政策,仔细分析了用于糖尿病管理的药物治疗情况,包括口服降糖药、注射疗法和辅助药物。此外,该研究还将糖尿病管理策略与乌干达国家发展计划(NDP)相结合,概述了医疗保健基础设施、加强初级保健、可持续融资、医疗信息系统和合作伙伴关系等方面的综合方法。关键词糖尿病 药用植物 乌干达 人种植物学 药理学评价 国家发展计划 综合医疗战略
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