Condyloma Accuminata In Pregnancy Overlapping With Bacterial Vaginosis

Septiana Widyantari, Dinda Rozita Maharani, Kinanthi Koesandrini, T. Setyaningrum
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Abstract

Background: Human Papilloma Virus (HPV) 6 and 11 are most commonly detected in genital warts, known as condyloma acuminata. Bacterial vaginosis (BV) is the most frequent vaginal infection in women aged 15 to 44 years. There may be an association between condyloma acuminata and BV. Purpose : To report a case of condyloma accuminata in a pregnant patient with combination bacterial vaginosis. Case: A 24-year-old, 8-week pregnant woman came to the clinic with a chief complaint of multiple warts in the genital area since 3 months prior to the hospital visit. The bumps on the vulva were small, and at first only one but then spread to surrounding areas. The bumps were itchy and painful. Complaints of vaginal discharge or fluor albus of yellowish-white gray color, accompanied by itchy and a fishy odor that appeared three months ago and worsened in the last two weeks. Examination results led to the diagnosis of condyloma acuminata and BV in the patient. The patient's condition improved after being given 90% trichloroacetic acid (TCA), electrocautery, and metronidazole. Discussion: Pregnancy decreases cell-mediated immunity, which may decrease immune tolerance and local physiologic changes and ultimately increase HPV infection in pregnancy. HPV infection is associated with a vaginal microbiota imbalance, making pregnant women prone to vaginal infections such as BV. Conclusion: Condyloma accuminata and BV often occur in high-risk groups for sexually transmitted infections, one of which is pregnant women. It is necessary to screen for sexually transmitted infections (STIs) in pregnant women to prevent complications.
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妊娠期合并细菌性阴道病的尖锐湿疣
背景:人类乳头瘤病毒(HPV)6 和 11 最常在生殖器疣(即尖锐湿疣)中检出。细菌性阴道病(BV)是 15 至 44 岁女性最常见的阴道感染。尖锐湿疣与 BV 之间可能存在关联。目的:报告一例合并细菌性阴道病的孕妇尖锐湿疣病例。病例:一名 24 岁、怀孕 8 周的孕妇前来就诊,主诉是自就诊前 3 个月起外阴部位出现多个尖锐湿疣。外阴上的疙瘩很小,起初只有一个,后来向周围扩散。疙瘩又痒又痛。主诉阴道分泌物或白带呈黄白灰色,伴有瘙痒和鱼腥味,三个月前出现,最近两周加重。检查结果确诊患者患有尖锐湿疣和阴道毛滴虫病。在给予 90% 三氯醋酸(TCA)、电灼和甲硝唑治疗后,患者的病情有所好转。讨论妊娠会降低细胞介导的免疫力,这可能会降低免疫耐受和局部生理变化,最终增加妊娠期的 HPV 感染。HPV 感染与阴道微生物群失衡有关,因此孕妇容易患阴道感染,如 BV。结论尖锐湿疣和 BV 常发生在性传播感染的高危人群中,孕妇就是其中之一。有必要对孕妇进行性传播感染筛查,以预防并发症的发生。
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