The effect of L. reuteri on Nonspecific Resistance and Hematological Parameters of Laboratory Animals

A. Ovcharova, N. V. Belova
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Abstract

Probiotics are microbial preparations, which have a positive effect on the composition of the intestinal microflora and the immune system of animals. These preparations are widely used for correcting and preventing violations of the microflora of the gastrointestinal tract. Lactobacilli play a special role in the formation of normal microflora. They exhibit a pronounced antagonistic activity against pathogenic and opportunistic microorganisms, as well as possess a number of other positive effects. This study is aimed at determining the effect of new probiotic strains of L. reuteri on the indicators of nonspecific resistance, hematological and biochemical parameters of laboratory rabbits. The studied strains were found to have a pronounced positive effect on the indicators of nonspecific resistance. Thus, compared to the control, the indicators of phagocytic activity and bactericidal activity in the experimental group were by 22% and 32% higher, respectively. The content of hemoglobin, erythrocytes and total protein in the blood serum also increased.
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纽崔莱对实验动物非特异性抵抗力和血液学参数的影响
益生菌是一种微生物制剂,对动物肠道微生物区系的组成和免疫系统有积极作用。这些制剂被广泛用于纠正和预防胃肠道微生物菌群失调。乳酸菌在正常微生物区系的形成过程中发挥着特殊作用。乳酸菌对病原微生物和机会性微生物具有明显的拮抗活性,并具有许多其他积极作用。本研究旨在确定新的 L. reuteri 益生菌株对实验兔的非特异性抵抗力指标、血液学和生化指标的影响。研究发现,所研究的菌株对非特异性抵抗力指标有明显的积极影响。因此,与对照组相比,实验组的吞噬活性和杀菌活性指标分别提高了 22% 和 32%。血清中的血红蛋白、红细胞和总蛋白含量也有所增加。
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