PREPARATION AND EXPERIMENTAL STUDY (IN VITRO) OF PURANDAR VATI

Kadambari A. Tupe, Ashvini Y. Deshmukh
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Abstract

Objective To prepare and evaluate the antimicrobial effect of Purandar vati (An Ayurvedic traditional formulation )against some of the bacterial stains. Method, Purandar vati was prepared using the classical reference of Bhaishajyaratnavali. Parada (Mercury) and Gandhaara (sulphur) were purified and then triturated to form Kajjali. Then raw drugs of Triphala and trikatu were converted into powder form, and all the ingredients were mixed and triturated with the help of aja dughdha (goat milk) and tablets were formed. The final product of Purandara vati was dried and stored. Antimicrobial activity of Purandar vati against streptococcus pneumonia and morxella catarrahlis bacteria was evaluated using the agar cup diffusion method. Result: Purandar vati shows a significant antibacterial spectrum against streptococcus pneumonia and morxella catarrahlis. Conclusion: This study shows that Purandara vati has antimicrobial potency and it can be clinically used for infectious respiratory disorders.
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普兰达尔瓦蒂的制备和实验研究(体外
目的 制备并评估 Purandar vati(一种阿育吠陀传统配方)对某些细菌污渍的抗菌效果。方法:使用 Bhaishajyaratnavali 的经典参考资料制备 Purandar vati。将 Parada(水银)和 Gandhaara(硫磺)提纯,然后经三蒸形成 Kajjali。然后将 Triphala 和 trikatu 原药转化为粉末状,在 aja dughdha(羊奶)的帮助下将所有成分混合并搅拌,形成药片。Purandara vati 的最终产品经过干燥和储存。使用琼脂杯扩散法评估了 Purandar vati 对肺炎链球菌和白喉摩沙菌的抗菌活性。结果显示Purandar vati 对肺炎链球菌和白喉摩沙菌具有明显的抗菌谱。结论这项研究表明,Purandara vati 具有抗菌效力,可用于临床治疗呼吸道感染性疾病。
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