Post-COVID Symptoms and Multisystem Inflammatory Syndrome in Children (MIS-C) in India: A Review

R. Santhoshkumar, K. R. Sathyaramanan, N. Venkateswaramurthy
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Abstract

This review article focuses on the post-COVID symptoms and Multisystem Inflammatory Syndrome in Children (MIS-C) observed in India. The study sheds light on the various clinical characteristics and outcomes associated with these conditions by examining available literature and data. The findings highlight the diverse range of symptoms experienced by children, including fever, gastrointestinal and respiratory manifestations, and skin rash. Additionally, rare observations such as HSP-like rash, gangrene, and arthritis were noted. The severity of MIS-C is evident, with a significant proportion of children experiencing shock and requiring mechanical ventilation. However, the review also emphasizes the favorable outcomes observed among children without preexisting comorbidities, indicating the potential for recovery in these cases. The review also provides reassuring findings regarding coronary outcomes during follow-up. This review underscores the urgent need for ongoing research, surveillance, and effective management strategies to address the long-term implications of post-COVID symptoms and MIS-C in Indian children. The insights presented in this article contribute to a better understanding of the impact of MIS-C and inform future strategies to mitigate its effects on the health and well-being of affected children in India.
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印度儿童 COVID 后症状和多系统炎症综合征 (MIS-C):综述
这篇综述文章的重点是在印度观察到的后COVID症状和儿童多系统炎症综合征(MIS-C)。研究通过对现有文献和数据的研究,揭示了与这些病症相关的各种临床特征和结果。研究结果强调了儿童所经历的各种症状,包括发热、胃肠道和呼吸道表现以及皮疹。此外,还发现了一些罕见的症状,如 HSP 样皮疹、坏疽和关节炎。MIS-C 的严重性显而易见,相当一部分患儿出现休克并需要机械通气。不过,综述也强调了在无并发症的患儿中观察到的良好结果,表明这些病例有康复的可能。综述还提供了令人欣慰的随访冠状动脉结果。这篇综述强调了对持续研究、监测和有效管理策略的迫切需要,以解决印度儿童 COVID 后症状和 MIS-C 的长期影响。本文提出的见解有助于更好地了解 MIS-C 的影响,并为未来减轻其对印度受影响儿童的健康和福祉的影响的策略提供参考。
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