VIROLOGICAL RESPONSE AND EFFECTIVENESS OF CHEMORADIATION THERAPY FOR ANAL CANCER: RELATIONSHIP AND PREDICTIVE CAPABILITIES

T. A. Zykova, M. Gusareva, E. A. Shevyakova, E. Frantsiyants, E.A. Tolmacheva, M. Zinkovich, N. G. Kosheleva, A. Solntseva
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Abstract

The effectiveness of chemoradiation therapy (CRT) is conventionally assessed in terms of achieving clinical complete response (CCR), overall and event-free survival. Anal cancer (AR) is considered as one of the cancer diseases with a proven etiological agent: the human papillomavirus (HPV). The search for biomarkers to predict the effectiveness of CRT is always relevant, and an assessment of virological response (VR) may be useful for this purpose. Aim: To compare rates of clinical complete response (CCR) and virological response (VR) to CRT for anal cancer.
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肛门癌的病毒学反应和化学放疗的有效性:关系和预测能力
化学放疗(CRT)的疗效通常根据临床完全反应(CCR)、总生存期和无事件生存期来评估。肛门癌(AR)被认为是已证实病原体为人类乳头瘤病毒(HPV)的癌症疾病之一。寻找预测 CRT 疗效的生物标志物一直都很重要,而病毒学应答(VR)评估可能对这一目的有用。目的:比较肛门癌 CRT 的临床完全应答率 (CCR) 和病毒学应答率 (VR)。
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来源期刊
Cardiometry
Cardiometry MEDICAL LABORATORY TECHNOLOGY-
自引率
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审稿时长
6 weeks
期刊介绍: Cardiometry is an open access biannual electronic journal founded in 2012. It refers to medicine, particularly to cardiology, as well as oncocardiology and allied science of biophysics and medical equipment engineering. We publish mainly high quality original articles, reports, case reports, reviews and lectures in the field of the theory of cardiovascular system functioning, principles of cardiometry, its diagnostic methods, cardiovascular system therapy from the aspect of cardiometry, system and particular approaches to maintaining health, engineering peculiarities in cardiometry developing. The interdisciplinary areas of the journal are: hemodynamics, biophysics, biochemistry, metrology. The target audience of our Journal covers healthcare providers including cardiologists and general practitioners, bioengineers, biophysics, medical equipment, especially cardiology diagnostics device, developers, educators, nurses, healthcare decision-makers, people with cardiovascular diseases, cardiology and engineering universities and schools, state and private clinics. Cardiometry is aimed to provide a wide forum for exchange of information and public discussion on above scientific issues for the mentioned experts.
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