Extreme hypernatraemia and rhabdomyolysis in a child with hyperosmolar hyperglycaemic state mixed with diabetic ketoacidosis

IF 0.5 Q4 ENDOCRINOLOGY & METABOLISM Practical Diabetes Pub Date : 2023-11-01 DOI:10.1002/pdi.2484
Christine Hesketh, Sinny Lau, Edward Holloway
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Abstract

Diabetic ketoacidosis (DKA) is present at diagnosis for about 40% of children with type 1 diabetes mellitus (DM).1 Hyperosmolar hyperglycaemic state (HHS) is another acute complication of DM more typically associated with type 2 DM in adults or adolescents. Recent evidence indicates that a mixed picture of HHS and DKA also occurs in children with type 1 DM2 but it is not frequently reported and therefore at risk of under‐recognition.
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一名患高渗性高血糖和糖尿病酮症酸中毒的儿童出现极度高钠血症和横纹肌溶解症
约 40% 的 1 型糖尿病(DM)患儿在确诊时已出现糖尿病酮症酸中毒(DKA)1。高渗高血糖状态(HHS)是糖尿病的另一种急性并发症,通常与成人或青少年的 2 型糖尿病有关。最近的证据表明,1 型糖尿病患儿也会出现高渗性高血糖状态和 DKA 的混合情况2 ,但这种情况并不常见,因此有可能得不到充分认识。
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来源期刊
Practical Diabetes
Practical Diabetes ENDOCRINOLOGY & METABOLISM-
CiteScore
1.10
自引率
16.70%
发文量
54
期刊介绍: Practical Diabetes concerns itself with all aspects of the worldwide clinical science and practice of diabetes medicine. The journal recognises the importance of each member of the healthcare team in the delivery of diabetes care, and reflects this diversity of professional interest in its editorial contents. The Editors welcome original papers, case reports, practice points, audit articles and letters on any aspect of clinical diabetes care from any part of the world. The journal also publishes commissioned leaders, review articles and educational and training series, for which an honorarium normally is paid. All articles submitted to Practical Diabetes are independently peer reviewed. They must not have been published or be under submission currently elsewhere. Enquiries from prospective authors are welcomed and the Editors will be pleased, if asked, to advise on preparation and submission of articles. All articles and enquiries should be directed to the Editors at the publishing address below. The journal is published nine times a year, and currently the average waiting time for acceptance of articles is eight weeks, and for subsequent publication sixteen weeks. Practical Diabetes is independent of any commercial or vested interest.
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