Comparative efficacy of three anesthetic protocols on cardiac parameters during ovary-hysterectomy in bitches

John Jaime Quimbaya Ramírez, Jessica Juliana Diaz Tarazona, Yudi Alejandra Gómez Toloza, Mariana De Gennaro, Yezid Alexander Ardila-Gómez, Víctor Gerardo Petro Hernández
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Abstract

This study aimed to compare the general electrical heart activity, blood pressure, and heart rate when using three anesthetic protocols for ovariohysterectomy in bitches. In total, 33 healthy canines were selected, distributed in 3 groups of 11 animals each, aged between 1 and 3 years, and with a body weight of 8 to 15 kg from shelters in Bucaramanga, Colombia. Three anesthetic protocols in a completely randomized experimental designwere used. Protocol 1: Ketamine (7 mg/kg) + pentobarbital sodium (1 mg/kg); Protocol 2: Ketamine (7 mg/kg) + propofol (3 mg/kg); Protocol 3: Tiletamine + zolazepam (7 mg/kg). The individual outcomes were classified according to the American Society of Anesthesiologists (ASA I). The results showed that parameters evaluated in the surgical phase significantly increased in patients with Protocol 1 (p<0.05). Protocol 2 showed a better performance in the post-surgical phase (p<0.05) compared with others. Patients with Protocol 3 presented fewer alterations in the electrical conduction of cardiac activity than the other protocols, and quicker recovery after the surgery.
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三种麻醉方案对母犬卵巢切除术中心脏参数的疗效比较
本研究旨在比较使用三种麻醉方案对母犬进行卵巢切除术时的一般心脏电活动、血压和心率。研究人员从哥伦比亚布卡拉曼加(Bucaramanga)的收容所共挑选了 33 只健康犬类,分为 3 组,每组 11 只,年龄在 1 到 3 岁之间,体重在 8 到 15 公斤之间。采用完全随机实验设计的三种麻醉方案。方案一:氯胺酮(7 毫克/千克)+戊巴比妥钠(1 毫克/千克);方案二:氯胺酮(7 毫克/千克)+丙泊酚(3 毫克/千克);方案三:氯胺酮+唑拉西泮(7 毫克/千克)。各项结果根据美国麻醉医师协会(ASA I)进行分类。结果显示,使用方案1的患者在手术阶段的评估参数明显增加(p<0.05)。与其他方案相比,方案 2 在手术后阶段的表现更好(p<0.05)。与其他方案相比,方案 3 患者的心脏活动电传导改变较少,术后恢复较快。
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