ASSESSMENT OF THE EFFECT OF DIFFERENT CLUSTERS OF THE METABOLIC SYNDROME ON THE EXPRESSION OF DEPRESSIVE DISORDERS

O. Moskalenko, I. Kasparova, R. Yaskevich
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Abstract

The purpose of the study. To study the influence of various metabolic syndrome clusters on the severity of depressive disorders according to the CES-D scale. Materials and methods. 136 male patients were examined, including 60 with metabolic syndrome. Metabolic syndrome was diagnosed based on the criteria of clinical recommendations of the All-Russian Scientific Society of Cardiology in 2009. The severity of depression was assessed using the Center for Epidemiological Studies Depression Scale - CES-D. Results. It was found that among the surveyed men with metabolic syndrome, depressive disorders of varying severity on the CES-D scale were found in 40% of the surveyed, while among men with MS, the number of people with severe depression on the CES-D scale was higher. Among persons with a four-component metabolic syndrome cluster, patients with severe depression were more common (57,1%). In men with depression on the CES-D scale of varying severity, a three-component cluster of metabolic syndromes was more common, consisting of abdominal obesity, arterial hypertension, and an elevated level of low-density lipoprotein cholesterol. Conclusion. The combination of abdominal obesity, arterial hypertension, and lipid disorders characterized by high levels of low-density lipoprotein was the most common metabolic syndrome cluster among men with depressive disorders of varying severity on the CES-D scale.
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评估代谢综合征不同组群对抑郁障碍表现的影响
研究目的根据 CES-D 量表研究各种代谢综合征群对抑郁障碍严重程度的影响。 材料和方法。研究对象为 136 名男性患者,其中 60 人患有代谢综合征。代谢综合征的诊断依据是 2009 年全俄罗斯心脏病学学会临床建议标准。抑郁症的严重程度使用流行病学研究中心抑郁量表(CES-D)进行评估。 结果显示结果发现,在接受调查的代谢综合征男性患者中,有40%的人患有CES-D量表中不同严重程度的抑郁症,而在多发性硬化症男性患者中,CES-D量表中患有严重抑郁症的人数较多。在患有四项代谢综合征的人群中,重度抑郁症患者更为常见(57.1%)。在 CES-D 量表中患有不同严重程度抑郁症的男性患者中,更常见的是三组代谢综合征,包括腹部肥胖、动脉高血压和低密度脂蛋白胆固醇水平升高。 结论是腹部肥胖、动脉高血压和以低密度脂蛋白胆固醇水平高为特征的血脂紊乱是根据CES-D量表患有不同严重程度抑郁障碍的男性中最常见的代谢综合征群。
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