The Effect of Traditional Jamu with Polyphenol-Rich Mixture Content on Cholesterol Levels in the Elderly with Coronary Heart Disease

Berliany Venny Sipollo, Sugiyanto, Elizabeth Yun, Yun Vinsur
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Abstract

Introduction: The aging process can impact the cardiovascular system in both structural and physiological ways, which can lead to atherosclerosis and an increased risk of coronary heart disease. While pharmacological interventions for CHD exist, they may come with unwanted side effects. As an alternative, many individuals turn to complementary medicine, including traditional herbal remedies. Among these remedies is a polyphenol-rich mixture (PRM) that has been shown to lower cholesterol levels and inhibit cholesterol absorption. Consequently, this study seeks to explore the efficacy of traditional herbal medicine containing PRM in reducing cholesterol levels in older adults with CHD. Methods: Design research uses quasi-experiment with two groups pre-test and post-test, the number of samples is 55 older adults with CHD, divided into 28 older adults consuming traditional herbal medicine and 27 older adults’ control. The researcher used an Accu-check to check the cholesterol level and analysed using a t-test. Results: The results showed that the decrease in mean cholesterol levels before and after the intervention period in the herbal medicine group (d = 50.50) was significantly greater than the mean score in the control group (d = -1.44) with p <.001. Conclusion: Older adults with coronary heart disease could benefit from traditional Jamu containing polyphenol-rich mixture by reducing cholesterol levels. This could be used as complementary medicine in nursing.
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富含多酚混合物的传统佳木对冠心病老人胆固醇水平的影响
引言衰老过程会从结构和生理两方面影响心血管系统,从而导致动脉粥样硬化,增加罹患冠心病的风险。虽然存在治疗冠心病的药物干预措施,但这些措施可能会带来不必要的副作用。作为一种替代方法,许多人转而采用补充医学,包括传统草药疗法。在这些疗法中,一种富含多酚的混合物(PRM)已被证明可以降低胆固醇水平并抑制胆固醇的吸收。因此,本研究试图探讨含有 PRM 的传统草药在降低患有心脏病的老年人胆固醇水平方面的功效。研究方法设计研究采用准实验法,分为前测和后测两组,样本数为 55 名患有心脏病的老年人,分为 28 名服用传统中药的老年人和 27 名对照组老年人。研究人员使用 Accu-Check 检测胆固醇水平,并使用 t 检验进行分析。结果显示结果显示,中药组干预前后胆固醇水平平均值的下降幅度(d = 50.50)明显大于对照组的平均值(d = -1.44),P <.001。结论患有冠心病的老年人可从含有丰富多酚混合物的传统佳木药中获益,降低胆固醇水平。这可作为护理中的辅助药物。
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