A Case Report of Intracranial Germ Cell Tumor-Induced Central Diabetes Insipidus in a Child Treated with Korean Herbal Medicine

Su Bin Park, Eun Hye Kim, Hayun Jin, Seong Woo Yoon
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Abstract

Objective: The purpose of this study is to report the case of intracranial germ cell tumor-induced central diabetes insipidus (CDI) in a child treated with Korean herbal medicine.Methods: A nine-year-old female patient diagnosed with intracranial germ cell tumor-induced CDI suffering from polyuria, polydipsia, and headache was hospitalized. Nocturia frequency and 24-hour urine volume were assessed.Results: The patient was treated with Korean medicine, including Nokyong-hwan. As a result of the 6-day inpatient treatment, nocturia frequency was decreased 3-4 times to 0-1 time, and 24-hour urine volume was decreased.Conclusion: Korean medicine, including Nokyong-hwan, may be considered an optional treatment for releasing the symptoms of intracranial germ cell tumor-induced CDI. Further studies are needed to confirm this finding.
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韩方草药治疗颅内生殖细胞瘤诱发儿童中枢性糖尿病的病例报告
研究目的本研究旨在报告一例用韩方中药治疗的颅内生殖细胞瘤诱发的儿童中枢性糖尿病(CDI)病例:一名 9 岁女性患者被诊断为颅内生殖细胞瘤诱发的 CDI,伴有多尿、多饮和头痛。对夜尿次数和 24 小时尿量进行了评估:结果:患者接受了包括能容丸在内的韩药治疗。住院治疗 6 天后,夜尿次数从 3-4 次减少到 0-1 次,24 小时尿量也有所减少:结论:包括能容丸在内的韩药可被视为缓解颅内生殖细胞肿瘤诱发的 CDI 症状的一种可选治疗方法。这一发现还需要进一步研究证实。
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