comparison of the relationship between inflammatory markers and saphenous vein graft disease in patients with stable angina pectoris

Abstract

BACKGROUND: Coronary artery bypass graft surgery is one of the most commonly used strategies to revascularization of occlusive coronary atherosclerotic lesions.Atherosclerosis is known to be a chronic inflammatory process. Many inflammatory cells and mechanisms are active in this process. AIM: Markers such as mean platelet volume-to-lymphocyte ratio (MPVLR) and C-reactive protein-to-albumin (CAR) which may be associated with the severity of inflammation.In this study,it was aimed to determine the relationship between these parameters and Saphenous Vein Graft (SVG) diseases. METHODS: In this retrospective study,314 patients SVG disease with stable angina pectoris were included. Patients were divided into two groups according to the severity of SVG disease.We compared 159 patients who had severe stenosis in SVG and 156 patients who did not,in terms of CAR, NLR, PLR, MPVLR. RESULTS: Patients who ≥50% stenosis in SVG had significantly higher CAR, MPVLR, NLR, and PLR (respectively 9.1 (4.2-16.8) p