The Effect of Okra (Abelmoschus esculentus) on the Hepatic Metabolism of Carbohydrates and Lipids

Abstract

Background and Objective: Okra ( Abelmoschus esculentus ) is one of the most popular and commonly used members of the Malvaceae family. The study investigated the phytochemical content of okra and its attendant metabolic role on the liver in maintaining the optimal concentrations of glucose and lipids in the body. Materials and Methods: Thirty albino rats divided into 5 groups (A, B, C, D and E) constituted the sample size as validated by mead’s equation. The control group was given sterile water, whereas okra extract of varying concentrations was given to the remaining four treatment groups. The administration was repeated daily for 4 weeks followed by anesthesia and then blood collection. Results: Data analysis was performed on SPSS version 21 software by using one-way ANOVA ( post hoc -LSD) statistical tool. The biochemical parameters analysed included liver chemistries, lipid profile, glucose and glycated haemoglobin using, WHO approved methods. The study revealed a significant decrease in concentrations of Aspartate Aminotransferase (AST), albumin and triacylglycerol, whereas other parameters were stable. Conclusion: Based on the results above, it could be concluded that A. esculentus enhances the metabolic role of the liver in maintaining the optimal concentrations of lipids and glucose in the body.