Rational Сhoice of Нepatoprotectors in the Treatment of Chronic Liver Diseases

S. N. Mekhtiev, O. A. Mekhtieva, O.M. Berko
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Abstract

The modern pharmacological industry provides healthcare professionals and patients with the widest choice of medicines (drugs) and biologically active additives. At the same time, the choice of the drug, in addition to the instructions for use and clinical recommendations, is influenced by personal experience of use (both the doctor and the patient), the cost of the drug, advertising and other factors. The Register of Medicines of Russia contains about 30 hepatoprotectors and their combinations, represented by more than 130 original drugs and their generics. This article presents data on the epidemiology of liver diseases in the world and in Russia, the general stages of the pathogenesis of liver lesions and the key points of application of drugs, as well as the role of a new hepatoprotector (a combination of ursodeoxycholic acid with glycyrrhizic acid) in the treatment of liver diseases
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在治疗慢性肝病时合理选择肝保护剂
现代制药业为医护人员和患者提供了最广泛的药品(药物)和生物活性添加剂选择。同时,除了使用说明和临床建议外,药物的选择还受到个人使用经验(医生和患者)、药物成本、广告和其他因素的影响。俄罗斯药品登记册》包含约 30 种保肝药及其复方制剂,由 130 多种原研药及其仿制药组成。本文介绍了世界和俄罗斯肝病流行病学数据、肝脏病变的一般发病阶段和药物应用要点,以及新型保肝药(熊去氧胆酸与甘草酸的复方制剂)在肝病治疗中的作用。
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