A comprehensive review on biogenically synthesized inorganic nanoparticles and their applications in anticancer activities

Zahra Barreto, Areej Fatima, Tuba Tariq, A. Zafar, M. S. Saif, Amina Zafar, Areeba Yousaf, Huang Xue, M. Hasan
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Abstract

The progression in nanotechnology has revolutionized the biomedical sciences for diagnosis and treatment of diseases like cancer. There have been many kinds of nanomaterials but Inorganic nanomaterials have been considered potential candidates for anticancer activities due to their high biocompatibility, less toxicity, high stability, and high precision in targeting affected cells. Several synthesis approaches have been used to prepared these nanoparticles, such as physical, chemical, and biogenic methods. Due to higher toxicity and adverse effects of chemical methods, eco-friendly way such as biosynthesized inorganic nanomaterials have attained much attention for multiple application particularly treatment of diseases. This review presents a comprehensive and updated knowledge (2015-2023) regarding the cancer treatment. The article first categorizes biogenically synthesized inorganic nanoparticles into three main groups: metallic nanoparticles, metal oxide nanoparticles, and quantum dots and then successful stories related to cancer treatment. This will also provide very effective platform for researchers and academia to detail the biogenically synthesized inorganic nanoparticles’ morphology, their characterization, targeted cancer cells.
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生物合成无机纳米粒子及其在抗癌活动中的应用综述
纳米技术的发展彻底改变了用于诊断和治疗癌症等疾病的生物医学科学。纳米材料有很多种,但无机纳米材料因其生物相容性好、毒性小、稳定性高、靶向受影响细胞的精确度高而被认为是抗癌活动的潜在候选材料。人们采用了多种合成方法来制备这些纳米粒子,如物理、化学和生物方法。由于化学方法的毒性和不良影响较大,生物合成无机纳米材料等生态友好型方法在多种应用领域,尤其是疾病治疗领域受到广泛关注。本综述全面介绍了有关癌症治疗的最新知识(2015-2023 年)。文章首先将生物合成的无机纳米粒子分为三大类:金属纳米粒子、金属氧化物纳米粒子和量子点,然后介绍了与癌症治疗相关的成功案例。这也将为研究人员和学术界详细介绍生物合成无机纳米粒子的形态、特性和靶向癌细胞提供非常有效的平台。
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