Determination of Prostate Specific Antigen Level among Male Patients with Bacterial Urinary Tract Infections Attending Kuje General Hospital Abuja, Nigeria

Abstract

Recent hospital and cancer registry data shows increasing prostate cancer incidence in Nigeria, which was previously regarded as a low incidence region. Prostate cancer is the leading cause of cancer death among men in Nigeria and second most common cancers of men worldwide and sexual history has been a consistent risk factor. Prostate specific antigen (PSA) test is still the single most important test for early detection of prostate cancer worldwide. However, not much is reported about prostate cancer in relation to urinary tract infections in Africa. This study investigates the prevalence of prostate cancer risk in and bacterial urinary tract infections among men in Abuja, Nigeria. One Hundred (100) samples each of blood and urine were collected, from fifty (50) male patients suffering from urinary tract infections and fifty (50) apparently healthy males attending Kuje General Hospital Abuja, Nigeria. All the blood samples were subjected to PSA analysis using Enzyme-linked Immunosorbent Assay procedure (Diagnostic Automation/ Cortez Diagnostics, Inc, USA) while urine analysis (microscopy, culture and biochemical identification) was performed on the urine to isolate and identify the common bacteria associated with urinary tract infections among the study population.