S. Voskanyan, V. L. Korobka, V. Syutkin, A. R. Monakhov, A. Maltseva, E. Pak, R. V. Korobka, E. I. Kolodyazhny, S. Zubenko, Yu. V. Voskanyan, V. Y. Kotsiyaev
{"title":"Development of graft-versus-host disease in a liver recipient. Clinical observations and literature review","authors":"S. Voskanyan, V. L. Korobka, V. Syutkin, A. R. Monakhov, A. Maltseva, E. Pak, R. V. Korobka, E. I. Kolodyazhny, S. Zubenko, Yu. V. Voskanyan, V. Y. Kotsiyaev","doi":"10.15825/1995-1191-2023-3-38-49","DOIUrl":null,"url":null,"abstract":"Graft-versus-host disease (GvHD) after liver transplantation (LT) occurs in 0.2–0.3% of liver transplant recipients. Each case is characterized by individual peculiarities of the clinical picture. There are no standards or clinical guidelines for the treatment of GvHD in solid organ recipients; mortality remains very high among these patients. We present two clinical cases of verified GvHD that developed early after LT, and we offer a brief review of the current state of the art in the study of this problem.","PeriodicalId":21400,"journal":{"name":"Russian Journal of Transplantology and Artificial Organs","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Transplantology and Artificial Organs","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15825/1995-1191-2023-3-38-49","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Graft-versus-host disease (GvHD) after liver transplantation (LT) occurs in 0.2–0.3% of liver transplant recipients. Each case is characterized by individual peculiarities of the clinical picture. There are no standards or clinical guidelines for the treatment of GvHD in solid organ recipients; mortality remains very high among these patients. We present two clinical cases of verified GvHD that developed early after LT, and we offer a brief review of the current state of the art in the study of this problem.
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