An Overview of Anti-diabetic Efficacy and Biochemical Mechanism of Anisomeles Malabarica (Malabar Catmint): A Review

Abstract

Diabetes mellitus (DM), which affects a substantial portion of the population and has become more common in modern society, is actually a metabolic condition. The hallmark of diabetes mellitus is excessively high blood sugar levels brought on by a breakdown in glucose homeostasis brought on by a partial or complete lack of insulin in the body or by insulin activity. Hyperglycaemia is caused by changes in insulin levels or activity as well as cell activities that affect the biochemical processes involved in the metabolism of carbohydrates, proteins, and lipids in target organs like the liver function. skeletal muscle, kidney, and adipose tissue. 1.5 million deaths per year are attributed to diabetes, and 48 percent of these fatalities occurring before the age of 70. Premature mortality from diabetes increased by 5% between the years 2000 and 2016. Therefore, it's essential to pick the appropriate diabetic therapy. Professional anti-diabetic medications are available to treat diabetes, however there are significant concerns over their cost and side effects. The drawbacks of currently available drugs necessitate the development of new, less expensive, and safer remedies. While Anisomeles malabarica (A. malabarica), an indigenous medicinal plant, has been shown to have anti-epileptic, anti-diabetic, anti-proliferative, and other qualities, the focus of this review is on AM's anti-diabetic advantages.