Ten Year Experience of Epidemiological Trends and Clinical Pattern of Vulvar Tumor

Diptajit Paul, Abhishek Soni, Sumit Chatterjee, Abhirup Chanda, Vivek Kaushal, Ashok Chauhan
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Abstract

Objectives: Vulvar tumor is a relatively uncommon female genito-urinary tumor, occurs mainly in post-menopausal females. Incidence and patterns of vulvar tumor differ from nation to nation, depending upon multiple factors. The aim of this study was to evaluate epidemiological patterns and clinical profile of vulvar tumor in our institution retrospectively. Methods: This is a retrospective study done in a regional cancer centre of India over10-years period. Data of all vulvar tumor patients, regarding demographic profile and tumor characteristics were collected from record section and reviewed. These data were analysed to get an idea about clinic-epidemiological trends of vulvar malignancy. Results: Total 47-patients with biopsy proven vulvar malignancy were found. Mean age at presentation was 63.4 years. Majority of the patients belonged to rural origin, were post-menopausal and multiparous. Most of them had pruritus as typical presenting symptoms. Histopathologically, squamous cell carcinoma constituted the major bulk. Labia was the commonest site of presentation. Bilateralism was found in one-third among them, inguinal lymphadenopathy and extensive disease were found in five and four patients, respectively. Conclusions: The hallmark about the present article is that it was conducted in the only referral cancer institute of this state. Limited studies from different region of India have published local patients’ data on vulvar tumor. A nationwide collaboration in this regard will help to understand the exact burden of this relatively rare malignancy, epidemiological trends and risk factors as well as an idea about how to manage these patients.
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外阴肿瘤流行趋势和临床模式的十年经验
目的:外阴肿瘤是一种较为少见的女性泌尿生殖系统肿瘤,主要发生于绝经后女性。外阴肿瘤的发病率和发病模式因国而异,取决于多种因素。本研究旨在对我院外阴肿瘤的流行病学模式和临床概况进行回顾性评估。研究方法这是一项在印度地区癌症中心进行的回顾性研究,历时 10 年。研究人员从记录部门收集并审查了所有外阴肿瘤患者的人口统计学特征和肿瘤特征数据。通过分析这些数据,了解外阴恶性肿瘤的临床流行趋势。结果:共发现 47 名经活检证实的外阴恶性肿瘤患者。平均发病年龄为 63.4 岁。大多数患者来自农村,绝经后且多产。大多数患者以瘙痒为典型症状。从组织病理学角度看,鳞状细胞癌占多数。阴唇是最常见的发病部位。其中三分之一的患者为双侧性,分别有五名和四名患者出现腹股沟淋巴结肿大和广泛病变。结论:本文的特点是在该邦唯一的癌症转诊机构进行的研究。印度不同地区公布的当地外阴肿瘤患者数据有限。这方面的全国性合作将有助于了解这种相对罕见的恶性肿瘤的确切负担、流行病学趋势和风险因素,以及如何管理这些患者。
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