Rapid assays of SARS-CoV-2 virus and noble biosensors by nanomaterials

IF 13.4 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Nano Convergence Pub Date : 2024-01-08 DOI:10.1186/s40580-023-00408-z

Yang Liu, Yilong Li, Yuteng Hang, Lei Wang, Jinghan Wang, Ning Bao, Youngeun Kim, Ho Won Jang

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Abstract

The COVID-19 outbreak caused by SARS-CoV-2 in late 2019 has spread rapidly across the world to form a global epidemic of respiratory infectious diseases. Increased investigations on diagnostic tools are currently implemented to assist rapid identification of the virus because mass and rapid diagnosis might be the best way to prevent the outbreak of the virus. This critical review discusses the detection principles, fabrication techniques, and applications on the rapid detection of SARS-CoV-2 with three categories: rapid nuclear acid augmentation test, rapid immunoassay test and biosensors. Special efforts were put on enhancement of nanomaterials on biosensors for rapid, sensitive, and low-cost diagnostics of SARS-CoV-2 virus. Future developments are suggested regarding potential candidates in hospitals, clinics and laboratories for control and prevention of large-scale epidemic.

Graphical Abstract

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用纳米材料快速检测 SARS-CoV-2 病毒和贵族生物传感器。

2019 年末，由 SARS-CoV-2 引起的 COVID-19 疫情在全球迅速蔓延，形成了一场全球性的呼吸道传染病疫情。目前正在加强对诊断工具的研究，以帮助快速识别病毒，因为大规模快速诊断可能是防止病毒爆发的最佳途径。本综述从快速核酸增强试验、快速免疫测定试验和生物传感器三个方面探讨了快速检测 SARS-CoV-2 的检测原理、制造技术和应用。特别是在生物传感器上改进纳米材料，以实现快速、灵敏和低成本的 SARS-CoV-2 病毒诊断。就医院、诊所和实验室控制和预防大规模流行病的潜在候选方案提出了未来发展建议。

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来源期刊

Nano Convergence Engineering-General Engineering

CiteScore

15.90

自引率

2.60%

发文量

审稿时长

13 weeks

期刊介绍： Nano Convergence is an internationally recognized, peer-reviewed, and interdisciplinary journal designed to foster effective communication among scientists spanning diverse research areas closely aligned with nanoscience and nanotechnology. Dedicated to encouraging the convergence of technologies across the nano- to microscopic scale, the journal aims to unveil novel scientific domains and cultivate fresh research prospects. Operating on a single-blind peer-review system, Nano Convergence ensures transparency in the review process, with reviewers cognizant of authors' names and affiliations while maintaining anonymity in the feedback provided to authors.