{"title":"A Case of Polyarteritis Nodosa and Antiphospholipid Antibody Positivity Presenting with Intramuscular Haematoma","authors":"Cheryl Chun Man Ng","doi":"10.1142/s2661341723720021","DOIUrl":null,"url":null,"abstract":"Polyarteritis nodosa (PAN) is a medium-sized vessel vasculitis often presenting report as both stenotic and aneurysmal lesions. Association with antiphospholipid antibody (aPL) has also been described. Here, we reported a case of PAN with history of cutaneous vasculitis presenting as multiple territory ischemic stroke, mesenteric panniculitis, coronary artery stenosis on imaging; lupus anticoagulant (LA) was also identified, patient was treated with immunosuppressants and anticoagulation. Disease course was, however, complicated by development of thigh haematoma. Clinical manifestation of PAN and its association with aPL will be discussed.","PeriodicalId":15538,"journal":{"name":"Journal of Clinical Rheumatology and Immunology","volume":"44 21","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Rheumatology and Immunology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1142/s2661341723720021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Polyarteritis nodosa (PAN) is a medium-sized vessel vasculitis often presenting report as both stenotic and aneurysmal lesions. Association with antiphospholipid antibody (aPL) has also been described. Here, we reported a case of PAN with history of cutaneous vasculitis presenting as multiple territory ischemic stroke, mesenteric panniculitis, coronary artery stenosis on imaging; lupus anticoagulant (LA) was also identified, patient was treated with immunosuppressants and anticoagulation. Disease course was, however, complicated by development of thigh haematoma. Clinical manifestation of PAN and its association with aPL will be discussed.
结节性多动脉炎(PAN)是一种中型血管炎,通常表现为血管狭窄和动脉瘤样病变。与抗磷脂抗体(aPL)相关的病例也有报道。在此,我们报告了一例有皮肤血管炎病史的 PAN 患者,表现为多部位缺血性中风、肠系膜泛发性炎、造影显示冠状动脉狭窄;还发现了狼疮抗凝物(LA),患者接受了免疫抑制剂和抗凝治疗。然而,大腿血肿的出现使病程变得复杂。本文将讨论 PAN 的临床表现及其与 aPL 的关联。