Informing Acceptability and Feasibility of Digital Phenotyping for Personalized HIV Prevention among Marginalized Populations Presenting to the Emergency Department.

Tiffany R Glynn, Simran S Khanna, Mohammad Adrian Hasdianda, Jeremiah Tom, Krishna Ventakasubramanian, Arlen Dumas, Conall O'Cleirigh, Charlotte E Goldfine, Peter R Chai
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Abstract

For marginalized populations with ongoing HIV epidemics, alternative methods are needed for understanding the complexities of HIV risk and delivering prevention interventions. Due to lack of engagement in ambulatory care, such groups have high utilization of drop-in care. Therefore, emergency departments represent a location with those at highest risk for HIV and in highest need of novel prevention methods. Digital phenotyping via data collected from smartphones and other wearable sensors could provide the innovative vehicle for examining complex HIV risk and assist in delivering personalized prevention interventions. However, there is paucity in exploring if such methods are an option. This study aimed to fill this gap via a cross-sectional psychosocial assessment with a sample of N=85 emergency department patients with HIV risk. Findings demonstrate that although potentially feasible, acceptability of digital phenotyping is questionable. Technology-assisted HIV prevention needs to be designed with the target community and address key ethical considerations.

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为在急诊科就诊的边缘化人群中开展个性化艾滋病毒预防工作提供数字表型的可接受性和可行性信息。
对于艾滋病毒持续流行的边缘化人群,需要采用其他方法来了解艾滋病毒风险的复杂性并提供预防干预措施。由于缺乏门诊护理,这些群体对临时护理的利用率很高。因此,急诊科是艾滋病风险最高、最需要新型预防方法的地方。通过智能手机和其他可穿戴传感器收集的数据进行数字表型分析,可为检查复杂的艾滋病风险提供创新工具,并有助于提供个性化的预防干预措施。然而,目前还缺乏对此类方法是否可行的探索。本研究旨在通过对 85 名急诊科艾滋病风险患者进行横断面社会心理评估来填补这一空白。研究结果表明,尽管数字表型具有潜在的可行性,但其可接受性仍值得商榷。技术辅助艾滋病预防需要与目标社区共同设计,并解决关键的伦理问题。
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