The role of red blood cell distribution width (RDW) in the diagnosis of pediatric sepsis.

The Turkish journal of pediatrics Pub Date : 2023-01-01 DOI:10.24953/turkjped.2023.182

Lingjun Xu, Lingfeng Yuan, Keqiang Chi, Dan Zhong, Liang Huang

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Abstract

Background: Early diagnosis of pediatric sepsis is difficult, so it is necessary to find a reliable auxiliary diagnostic method. The purpose of the study was to assess the role of RDW in the diagnosis of pediatric sepsis.

Methods: We did a case control study reviewing pediatric inpatients (≥28 days, < 18 years old) who were diagnosed with sepsis between April 2020 and November 2022. According to the sepsis-3 and Pediatric Sequential Organ Failure Assessment (pSOFA) scoring standards, 66 septic inpatients of the pediatric intensive care unit (PICU) were included in the sepsis group and 66 non-septic inpatients of the PICU were included by using the random sampling method during the same period as the control group.

Results: RDW values in the sepsis group were higher than those in the control group (P < 0.001). The cut-off value, sensitivity, specificity and area under curve of RDW for sepsis were 39.15, 0.955, 0.758 and 0.943,respectively.

Conclusions: Our study confirms that RDW may have a good value on the early diagnosis of pediatric sepsis.

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红细胞分布宽度（RDW）在诊断小儿败血症中的作用。

背景：小儿败血症的早期诊断非常困难，因此有必要找到一种可靠的辅助诊断方法。本研究旨在评估 RDW 在诊断小儿败血症中的作用：我们对 2020 年 4 月至 2022 年 11 月期间被诊断为败血症的儿科住院患者（≥28 天，年龄小于 18 岁）进行了病例对照研究。根据脓毒症-3和儿科序贯器官功能衰竭评估（pSOFA）评分标准，将儿科重症监护室（PICU）的66名脓毒症住院患者纳入脓毒症组，并采用随机抽样方法将同期儿科重症监护室的66名非脓毒症住院患者纳入对照组：败血症组的 RDW 值高于对照组（P<0.001）。脓毒症组 RDW 的临界值、敏感性、特异性和曲线下面积分别为 39.15、0.955、0.758 和 0.943：我们的研究证实，RDW 对小儿败血症的早期诊断有很好的价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Turkish journal of pediatrics

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