Metastatic ovarian high grade serous carcinoma with intestinal and omental deposits and marked clinicopathological treatment response in right ovary: A rare case report

Abstract

High grade serous ovarian cancer is the most common form of ovarian cancer which is frequently fatal, as it is commonly diagnosed after substantial metastasis has already occurred. The present study reports a 65 years old woman with postmenopausal bleeding for 3 months. CE-MRI revealed malignant right ovarian lesion with broad ligament fibroid with malignant degeneration. Histopathological examination was consistent with high grade serous carcinoma of right ovary. Patient then received 6 cycles of chemotherapy. After 4 months, she developed abdominal discomfort and backache for which a repeat CE-MRI was performed which showed a heterogeneity in the right adnexa with no markedly appreciable abnormal foci in the right ovary. Subsequently the patient underwent transabdominal hysterectomy with bilateral salpingo-oophorectomy with right hemicolectomy and omentectomy. Microscopic examination of intestine and omentum showed infiltration by tumor cells. A final diagnosis of metastatic high grade carcinoma of ovary with intestinal and omental deposits was given.