Vishal Chaudhary, S. Rustagi, Ajeet Kumar Kaushik, Manisha Bhutani
{"title":"Prospect of Nano-Enabled Optical Biosensors for Antibiotic Abuse Surveillance as an Early Prevention Tool for Antimicrobial Resistance","authors":"Vishal Chaudhary, S. Rustagi, Ajeet Kumar Kaushik, Manisha Bhutani","doi":"10.1149/2162-8777/ad1c8d","DOIUrl":null,"url":null,"abstract":"\n Antimicrobial resistance (AMR) in humans is driven by pragmatic contagion diagnostics and incessant inadvertent antibiotics abuse (AB). The state-of-the-art AB monitoring involves developing nanomaterials-enabled optical biosensors with prompt and precise detection efficacy. This prospect highlights the diversified optical biosensors, including SPR, SERS, and fluorescent and colorimetric biosensors, for efficiently detecting AB. It also elaborates the fundamentals, challenges, potential alternatives, and prospects associated with these optical biosensing strategies for detecting AB as an effective AMR prevention/monitoring strategy. This will serve as a roadmap for future research and development dedicated to nano-enabled-optical biosensors for AMR monitoring through AB detection at community/individual sources.","PeriodicalId":504734,"journal":{"name":"ECS Journal of Solid State Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ECS Journal of Solid State Science and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1149/2162-8777/ad1c8d","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Antimicrobial resistance (AMR) in humans is driven by pragmatic contagion diagnostics and incessant inadvertent antibiotics abuse (AB). The state-of-the-art AB monitoring involves developing nanomaterials-enabled optical biosensors with prompt and precise detection efficacy. This prospect highlights the diversified optical biosensors, including SPR, SERS, and fluorescent and colorimetric biosensors, for efficiently detecting AB. It also elaborates the fundamentals, challenges, potential alternatives, and prospects associated with these optical biosensing strategies for detecting AB as an effective AMR prevention/monitoring strategy. This will serve as a roadmap for future research and development dedicated to nano-enabled-optical biosensors for AMR monitoring through AB detection at community/individual sources.
人类的抗菌药耐药性(AMR)是由实用的传染病诊断和不断滥用抗生素(AB)造成的。最先进的抗生素滥用监测包括开发具有快速、精确检测功效的纳米材料光学生物传感器。本展望重点介绍了用于有效检测 AB 的各种光学生物传感器,包括 SPR、SERS 以及荧光和比色生物传感器。它还阐述了与这些光学生物传感策略相关的基本原理、挑战、潜在替代方案和前景,以检测 AB 作为一种有效的 AMR 预防/监测策略。这将为今后通过在社区/个人源头检测 AB 来监测 AMR 的纳米光学生物传感器的研发工作提供路线图。