Anne-Marie Beatrice Poenariu, Roberto Angelo Postelnicu, M. Ciocîlteu, Gabriela Rau, Mariana Popescu, A. Simionescu, Ionela Andreea Neacsu, C. Nicolicescu, D. Amzoiu
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引用次数: 0
Abstract
Combining polimers with polyphenols such as gallic acid opens up new directions in healthcare system. By encapsulating secondary metabollites within PLGA nanoparticles, we tried to enhance their stability, solubility, and obtain a targeted delivery system. In this study, we synthesized a PLGA-gallic acid sustained release system, using the solvent evaporation method. This approach improved the therapeutic efficacy of gallic acid. The numerical distribution showed that most PLGA-GA nanoparticles have a size of 10 nm. Through the method of solvent evaporation, an incorporation efficiency of 49% was obtained.
期刊介绍：
Materiale Plastice, abbreviated as Mater. Plast., publishes original scientific papers or guest reviews on topics of great interest.
The Journal does not publish memos, technical reports or non-original papers (that are a compiling of literature data) or papers that have been already published in other national or foreign Journal.
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