Corticosteroid injection in the treatment of a huge-size central giant cell granuloma in children: A case report

Abstract

Central giant cell granulomas (CGCGs) of the jaw are benign intraosseous and osteolytic lesions. Their clinical presentation includes atypical aggressive lesions that cause severe damage early in life, and aggressive treatment is necessary in most cases to prevent recurrence. Curettage is the most preferred therapy, but in recent years, conservative therapy is also commonly used. Corticosteroid injection treatment, a conservative method, was planned for a developing male patient with difficulty in diagnosis and treatment due to the complications of resection. After clinical and radiologic evaluation of the patient, incisional biopsy was performed and the diagnosis of SDHG was made. The patient was treated with intralesional corticosteroids once a week for eight weeks. Since the patient's treatment was interrupted for 2 months due to the Covid-19 outbreak, 2 doses of intralesional corticosteroid (Sinakort-A 40 mg) were administered and the patient was followed up. At 12 months, clinical and panoramic radiographic examination revealed no pathologic findings related to the lesion. In this article, we report a pediatric case of giant CGCG successfully treated with intralesional corticosteroid injection.