Blood-brain barrier transporters: a translational consideration for CNS delivery of neurotherapeutics

IF 5 2区 医学 Q1 PHARMACOLOGY & PHARMACY Expert Opinion on Drug Delivery Pub Date : 2024-01-13 DOI:10.1080/17425247.2024.2306138
Patrick T. Ronaldson, Thomas P. Davis
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Abstract

Successful neuropharmacology requires optimization of CNS drug delivery and, by extension, free drug concentrations at brain molecular targets. Detailed assessment of blood-brain barrier (BBB) phys...
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血脑屏障转运体:中枢神经系统输送神经治疗药物的转化考量
成功的神经药理学需要优化中枢神经系统的给药,进而优化脑分子靶点的游离药物浓度。对血脑屏障(BBB)物理特性的详细评估可以帮助研究人员更好地了解中枢神经系统的药物输送和药物在脑部分子靶点的游离浓度。
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来源期刊
CiteScore
11.10
自引率
3.00%
发文量
104
审稿时长
3 months
期刊介绍: Expert Opinion on Drug Delivery (ISSN 1742-5247 [print], 1744-7593 [electronic]) is a MEDLINE-indexed, peer-reviewed, international journal publishing review articles covering all aspects of drug delivery research, from initial concept to potential therapeutic application and final relevance in clinical use. Each article is structured to incorporate the author’s own expert opinion on the scope for future development.
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