Development, Construction, and Evaluation of an Alternative Dosimetry Phantom for Computed Tomography.

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Medical Physics Pub Date : 2023-10-01 Epub Date: 2023-12-05 DOI:10.4103/jmp.jmp_92_23
Lukmanda Evan Lubis, Windi Dliya Najmah, Yuni Muliyanti, Ika Hariyati, Dea Ryangga, Terry Mart, Hilde Bosmans, Djarwani Soeharso Soejoko
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Abstract

This article aims to present the development, construction, and evaluation of an alternative computed tomography dose index (CTDI) phantom. Epoxy resin was mixed with an iodine-based contrast agent to produce radiological characteristics resembling polymethyl methacrylate (PMMA) as a standard CTDI phantom. As a preliminary study, testing was carried out using computed tomography images (80 and 120 kVp) on 12 variations of epoxy-iodine resin mixtures to obtain relative electron density (ρe) values and effective atomic numbers (Zeff) of the samples. The alternative CTDI phantoms were then constructed with a resin-iodine mixture using iodine concentrations that yield on closest ρe and Zeff values to those of PMMA. The evaluation was carried out by comparing dose measurement results at various energies between the alternative phantom and the International Electrotechnical Commission-standard CTDI phantom. At a concentration of 0.46%, the epoxy resin has ρe and Zeff with a deviation against PMMA of 0.12% and 1.58%, respectively, so that composition was chosen for the alternative CTDI phantom construction. The average dose discrepancy values were 5% and 1%, respectively, for the head and body phantoms in the tested tube voltages of 80 kVp, 100 kVp, 120 kVp, and 135 kVp. The Student's t-test result between the alternative and the standard phantoms also showed P < 0.05, indicating the comparability of the alternative CTDI phantom with the standard CTDI phantom.

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开发、构建和评估用于计算机断层扫描的替代剂量测定模型。
本文旨在介绍一种替代性计算机断层扫描剂量指数(CTDI)模型的开发、构建和评估。环氧树脂与碘基造影剂混合,产生了类似于聚甲基丙烯酸甲酯(PMMA)的放射学特征,作为标准 CTDI 模型。作为初步研究,使用计算机断层扫描图像(80 和 120 kVp)对 12 种环氧-碘树脂混合物进行了测试,以获得样品的相对电子密度 (ρe)值和有效原子序数 (Zeff)。然后用树脂-碘混合物构建了替代 CTDI 模型,使用的碘浓度产生了最接近 PMMA 的 ρe 和 Zeff 值。通过比较替代模型和国际电工委员会标准 CTDI 模型在不同能量下的剂量测量结果,进行了评估。在浓度为 0.46% 时,环氧树脂的 ρe 和 Zeff 与 PMMA 的偏差分别为 0.12% 和 1.58%,因此该成分被选为 CTDI 模型的替代成分。在 80 kVp、100 kVp、120 kVp 和 135 kVp 的测试管电压下,头部和身体模型的平均剂量差异值分别为 5%和 1%。替代模型与标准模型之间的学生 t 检验结果也显示 P < 0.05,表明替代 CTDI 模型与标准 CTDI 模型具有可比性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Medical Physics
Journal of Medical Physics RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.10
自引率
11.10%
发文量
55
审稿时长
30 weeks
期刊介绍: JOURNAL OF MEDICAL PHYSICS is the official journal of Association of Medical Physicists of India (AMPI). The association has been bringing out a quarterly publication since 1976. Till the end of 1993, it was known as Medical Physics Bulletin, which then became Journal of Medical Physics. The main objective of the Journal is to serve as a vehicle of communication to highlight all aspects of the practice of medical radiation physics. The areas covered include all aspects of the application of radiation physics to biological sciences, radiotherapy, radiodiagnosis, nuclear medicine, dosimetry and radiation protection. Papers / manuscripts dealing with the aspects of physics related to cancer therapy / radiobiology also fall within the scope of the journal.
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