Mechanism of infection of SARS-CoV-2 and gender based differential impacts

D. Ghosh, Suvendu Ghosh, P. Singha
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Abstract

The world has witnessed a pandemic in the recent past. COVID-19 has been a nightmare for all. The virus SARS-CoV-2 causes the disease. The impact of the pandemic on human life and on various aspects of the society is still prevailing. No specific effective drug has yet been formulated to completely combat the virus. It took more than a year for the researchers and scientists around the globe to understand the mechanism of the virus infection. For the time being vaccines have been designed and those seems to be effective in preventing the infection to some extent. The pattern of infection by SARS-CoV-2, symptoms, pathophysiology, complications and fatality associated with COVID-19 has been found to be dependent on various factors and varies from person to person. The virus has been found to have differential mechanism of infection and impacts in male and female. The X-Chromosome plays an interesting role.
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SARS-CoV-2 的感染机制和基于性别的不同影响
不久前,世界上发生了一场大流行病。COVID-19 是所有人的噩梦。这种疾病是由 SARS-CoV-2 病毒引起的。这一大流行病对人类生活和社会各方面的影响仍然普遍存在。至今还没有一种特效药物可以完全对付这种病毒。全球的研究人员和科学家花了一年多的时间才弄清病毒感染的机理。目前,人们已经设计出了疫苗,这些疫苗似乎在一定程度上可以有效预防感染。与 COVID-19 相关的 SARS-CoV-2 感染模式、症状、病理生理学、并发症和致死率取决于各种因素,而且因人而异。已发现该病毒对男性和女性的感染和影响机制不同。X 染色体发挥着有趣的作用。
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