Authorization of anastrazole to prevent breast cancer in postmenopausal women: a bad idea.

IF 2.9 4区 医学 Q1 OBSTETRICS & GYNECOLOGY Climacteric Pub Date : 2024-04-01 Epub Date: 2024-01-24 DOI:10.1080/13697137.2023.2297889
S J Glynne, A Z Bluming
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Abstract

Anastrazole has recently been approved for the prevention of breast cancer in high-risk women in the UK. When given to high-risk women anastrazole halves the risk of developing breast cancer but doesn't reduce the risk of breast cancer death and is associated with significant harms. Women need to be counselled about both the benefits and risks associated with anastrazole use to enable an informed treatment choice.

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授权阿那曲唑用于绝经后妇女预防乳腺癌:一个坏主意。
阿那曲唑最近被批准用于预防英国高危妇女患乳腺癌。高危妇女服用阿那曲唑后,罹患乳腺癌的风险会降低一半,但不会降低乳腺癌死亡的风险,而且会带来很大的危害。需要就使用阿那曲唑的益处和风险向妇女提供咨询,以便她们做出明智的治疗选择。
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来源期刊
Climacteric
Climacteric 医学-妇产科学
CiteScore
1.70
自引率
7.10%
发文量
53
审稿时长
1 months
期刊介绍: Climacteric is the official journal of the International Menopause Society (IMS). As an international peer-reviewed journal it publishes original research and reviews of all aspects of aging in women. Climacteric was founded by the IMS in 1998 and today has become a leading journal in the publication of peer-reviewed papers on the menopause, climacteric and mid-life health. Topics covered include endocrine changes, symptoms attributed to the menopause and their treatment, hormone replacement and alternative therapies, lifestyles, and the counselling and education of peri- and postmenopausal women. Climacteric, published bimonthly, also features regular invited reviews, editorials and commentaries on recent developments. The editorial review board of Climacteric includes leading scientific and clinical experts in the field of midlife medicine and research and is headed by its Editor-in-Chief, Professor Rod Baber of Australia. He and his team of Associate Editors act independently to set a clear editorial policy, co-ordinate peer review, and ensure a rapid response to submitted papers.
期刊最新文献
Hyperandrogenism after menopause: diagnostic evaluation. Factors influencing seogeulpeum among middle-aged Korean women. Perimenopausal combined hormonal contraception: focus on sexual function. Systemic hormone therapy after breast and gynecological cancers: an Italian expert group consensus opinion. Hyaluronic acid and erbium laser for the treatment of genitourinary syndrome of menopause.
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