Bilateral Involvement of Age-Related Macular Degeneration in South Korea: Findings from the Korea National Health and Nutrition Examination Survey 2017-2020.

IF 1.7 4区 医学 Q3 OPHTHALMOLOGY Ophthalmic epidemiology Pub Date : 2024-10-01 Epub Date: 2024-01-24 DOI:10.1080/09286586.2023.2301583
Yeji Kim, Mi Yeon Song, Kyungdo Han, Jae Hui Kim
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Abstract

Purpose: To evaluate the bilateral involvement of age-related macular degeneration (AMD) in South Koreans.

Methods: This was a cross-sectional study of the Korean National Health and Nutrition Examination Survey (2017-2020). This study included 13,737 participants aged 40 years or older. Participants were evaluated to determine the prevalence of bilateral early and late AMD. In cases in which exudative AMD or geographic atrophy (GA) was diagnosed in a single eye, the fellow eye was evaluated to determine the presence and type of late AMD.

Results: The overall prevalence of bilateral AMD was 6.12% (95% confidence interval [CI], 5.63-6.61). The prevalence of bilateral early AMD was 5.71% (95% CI, 5.24-6.18), while that of late AMD was 0.14% (95% CI, 0.08-0.20). The prevalence of the bilateral involvement of late AMD increased with age. A 0.02% prevalence (95% CI, 0.00-0.06) of late AMD was observed in participants aged 50-59. The prevalence increased to 0.08% (95% CI, 0.00-0.18) in participants aged 60-69, while the prevalence in participants aged 70-79 and over 80 was 0.45% (95% CI, 0.12-0.78) and 1.97% (95% CI, 0.75-3.19), respectively. The prevalence of early AMD in one eye and late AMD in the fellow eye was 0.26% (95% CI, 0.16-0.36).

Conclusions: An assessment of the incidence of AMD revealed that a significant number of persons had bilateral involvement. The treatment burden may significantly increase for participants with bilateral late AMD compared to those with unilateral involvement. Therefore, the study may be helpful with the establishment of private and national insurance policies.

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韩国老年性黄斑变性的双侧累及情况:2017-2020年韩国国民健康与营养调查》。
目的:评估韩国人老年性黄斑变性(AMD)的双侧累及情况:这是一项韩国国民健康与营养调查(2017-2020 年)的横断面研究。这项研究包括 13737 名 40 岁或以上的参与者。对参与者进行了评估,以确定双侧早期和晚期 AMD 的患病率。如果单眼诊断出渗出性老年黄斑病变或地理萎缩(GA),则对同侧眼进行评估,以确定是否存在晚期老年黄斑病变及其类型:结果:双侧 AMD 的总患病率为 6.12%(95% 置信区间 [CI],5.63-6.61)。双侧早期 AMD 患病率为 5.71%(95% 置信区间,5.24-6.18),而晚期 AMD 患病率为 0.14%(95% 置信区间,0.08-0.20)。双侧受累的晚期 AMD 患病率随年龄增长而增加。在 50-59 岁的参与者中,晚期 AMD 的患病率为 0.02%(95% CI,0.00-0.06)。在 60-69 岁的参与者中,患病率增至 0.08%(95% CI,0.00-0.18),而在 70-79 岁和 80 岁以上的参与者中,患病率分别为 0.45%(95% CI,0.12-0.78)和 1.97%(95% CI,0.75-3.19)。单眼早期AMD和双眼晚期AMD的发病率分别为0.26%(95% CI,0.16-0.36):结论:对AMD发病率的评估显示,相当多的人是双眼受累。与单侧受累者相比,双侧晚期AMD患者的治疗负担可能会明显加重。因此,这项研究可能有助于制定私人和国家保险政策。
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来源期刊
Ophthalmic epidemiology
Ophthalmic epidemiology 医学-眼科学
CiteScore
3.70
自引率
5.60%
发文量
61
审稿时长
6-12 weeks
期刊介绍: Ophthalmic Epidemiology is dedicated to the publication of original research into eye and vision health in the fields of epidemiology, public health and the prevention of blindness. Ophthalmic Epidemiology publishes editorials, original research reports, systematic reviews and meta-analysis articles, brief communications and letters to the editor on all subjects related to ophthalmic epidemiology. A broad range of topics is suitable, such as: evaluating the risk of ocular diseases, general and specific study designs, screening program implementation and evaluation, eye health care access, delivery and outcomes, therapeutic efficacy or effectiveness, disease prognosis and quality of life, cost-benefit analysis, biostatistical theory and risk factor analysis. We are looking to expand our engagement with reports of international interest, including those regarding problems affecting developing countries, although reports from all over the world potentially are suitable. Clinical case reports, small case series (not enough for a cohort analysis) articles and animal research reports are not appropriate for this journal.
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