Exposure to mixtures of PM_2.5 components and term premature rupture of membranes: a case-crossover study in Shijiazhuang, China.

IF 2.2 4区医学 Q3 ENVIRONMENTAL SCIENCES International Journal of Environmental Health Research Pub Date : 2024-01-25 DOI:10.1080/09603123.2024.2308017

Weiyan Ren, Huangmin Yang, Wencong Liu, Shaochong Zhang, Yanjing Yang, Lei Yang, Wenxuan Liu, Haijuan Zhang, Ke He, Xia Li, Jun Ge

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Abstract

This study aims to explore the acute effects of short-term exposure to PM_2.5 components and their mixture on PROM. Counts of hospital admissions due to PROM were collected at the Fourth Hospital of Shijiazhuang. The associations between the PROM and PM_2.5 components was examined using a time-stratified case-crossover approach. The overall effects of components on TPROM were examined using the BKMR. During the study period 30,709 cases of PROMwere identified. The relative risks and the 95% CI of TPROM were 1.013 (1.002, 1.028) and 1.015 (1.003, 1.028) associated with per interquartile range increase in nitrate and ammonium ion on the current day and they were 1.007 (1.001, 1.013) and 1.003 (1.000, 1.005) on the previous day. The results from the BKMR models showed a higher risk of TPROM was associated with exposure to mixtures, in which, nitrate and organic matter were the main contributors to the overall effect.

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接触 PM2.5 混合物与胎膜早破：中国石家庄的病例交叉研究。

本研究旨在探讨短期暴露于PM2.5成分及其混合物对PROM的急性影响。在石家庄市第四医院收集了因PROM而入院的人数。采用时间分层病例交叉法研究了PROM与PM2.5成分之间的关系。使用BKMR检验了各组分对TPROM的总体影响。在研究期间，共发现了 30 709 例 PROM。当日硝酸盐和铵离子的相对风险和 95% CI 分别为 1.013 (1.002, 1.028) 和 1.015 (1.003, 1.028)，而前一天硝酸盐和铵离子的相对风险和 95% CI 分别为 1.007 (1.001, 1.013) 和 1.003 (1.000, 1.005)。BKMR 模型的结果显示，较高的 TPROM 风险与接触混合物有关，其中硝酸盐和有机物是造成总体影响的主要因素。

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来源期刊

International Journal of Environmental Health Research 医学-公共卫生、环境卫生与职业卫生

CiteScore

6.70

自引率

3.10%

发文量

134

审稿时长

>12 weeks

期刊介绍： International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.