Musculoskeletal involvement in neglected tropical diseases: a comprehensive review.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-01-25 DOI:10.1007/s00256-024-04595-6

Aline Serfaty, Tatiane Cantarelli Rodrigues

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Abstract

Neglected tropical diseases (NTDs) encompass a group of diseases predominantly found in tropical regions, with origins dating back to their inclusion in the United Nations Millennium Development Goals in 2000. This initiative aimed to raise awareness and global funding to combat these diseases, which thrive in areas with limited sanitation, healthcare, and education. NTDs are caused by various pathogens such as bacteria, fungi, parasites, and viruses and affect over two billion individuals in resource-poor communities, leading to preventable deaths and devastating consequences. While the musculoskeletal system is only occasionally affected, the resulting chronic disabilities prevent individuals from working, posing a significant socioeconomic burden in this region of the world. Some NTDs exhibit distinct imaging features, and radiologists need to be aware of these characteristics to facilitate early treatment. In this review, we delve into musculoskeletal NTDs, focusing on clinical features and imaging findings, differential diagnosis, and clinical management.

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被忽视的热带疾病中的肌肉骨骼问题：全面综述。

被忽视的热带疾病（NTDs）包括一组主要发生在热带地区的疾病，其起源可追溯到 2000 年被纳入联合国千年发展目标。该倡议旨在提高人们对这些疾病的认识，并在全球范围内筹集资金，以防治这些在卫生条件、医疗保健和教育有限的地区肆虐的疾病。非传染性疾病由细菌、真菌、寄生虫和病毒等各种病原体引起，影响着资源匮乏社区的 20 多亿人，导致可预防的死亡和破坏性后果。虽然肌肉骨骼系统只是偶尔受到影响，但由此导致的慢性残疾使人们无法工作，给世界上这一地区造成了巨大的社会经济负担。一些 NTD 表现出明显的影像学特征，放射科医生需要了解这些特征，以便及早治疗。在这篇综述中，我们将深入研究肌肉骨骼类 NTD，重点关注临床特征和影像学发现、鉴别诊断和临床治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.

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