Drug and Natural Health Product Data Collection and Curation in the Canadian Longitudinal Study on Aging.

IF 1.7 4区医学 Q3 GERONTOLOGY Canadian Journal on Aging-Revue Canadienne Du Vieillissement Pub Date : 2024-01-25 DOI:10.1017/S0714980823000806

Benoit Cossette, Lauren Griffith, Patrick D Emond, Dee Mangin, Lorraine Moss, Jennifer Boyko, Kathryn Nicholson, Jinhui Ma, Parminder Raina, Christina Wolfson, Susan Kirkland, Lisa Dolovich

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Abstract

This study aimed to develop an efficient data collection and curation process for all drugs and natural health products (NHPs) used by participants to the Canadian Longitudinal Study on Aging (CLSA). The three-step sequential process consisted of (a) mapping drug inputs collected through the CLSA to the Health Canada Drug Product Database (DPD), (b) algorithm recoding of unmapped drug and NHP inputs, and (c) manual recoding of unmapped drug and NHP inputs. Among the 30,097 CLSA comprehensive cohort participants, 26,000 (86.4%) were using a drug or an NHP with a mean of 5.3 (SD 3.8) inputs per participant user for a total of 137,366 inputs. Of those inputs, 70,177 (51.1%) were mapped to the Health Canada DPD, 20,729 (15.1%) were recoded by algorithms, and 44,108 (32.1%) were manually recoded. The Direct algorithm correctly classified 99.4 per cent of drug inputs and 99.5 per cent of NHP inputs. We developed an efficient three-step process for drug and NHP data collection and curation for use in a longitudinal cohort.

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加拿大老龄化纵向研究中的药物和天然保健品数据收集与整理。

本研究旨在为加拿大老龄化纵向研究（CLSA）参与者使用的所有药物和天然保健品（NHPs）开发一种高效的数据收集和整理流程。三步顺序流程包括：（a）将通过 CLSA 收集的药物输入映射到加拿大卫生部药物产品数据库 (DPD)；（b）对未映射的药物和 NHP 输入进行算法重新编码；以及（c）对未映射的药物和 NHP 输入进行人工重新编码。在 30,097 名 CLSA 综合队列参与者中，26,000 人（86.4%）正在使用一种药物或一种 NHP，每个参与者用户平均输入 5.3 次（标准差 3.8 次），总计输入 137,366 次。在这些输入中，70,177 项（51.1%）被映射到加拿大卫生部 DPD，20,729 项（15.1%）被算法重新编码，44,108 项（32.1%）被人工重新编码。直接算法正确分类了 99.4% 的药物输入和 99.5% 的非活体输入。我们开发了一套高效的三步流程，用于药物和非生物制品数据的收集和整理，以便在纵向队列中使用。

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来源期刊

Canadian Journal on Aging-Revue Canadienne Du Vieillissement GERONTOLOGY-

CiteScore

3.40

自引率

5.30%

发文量

109

期刊介绍： The Canadian Journal on Aging/La Revue canadienne du vieillissement (CJA/RCV) promotes excellence in research and disseminates the latest work of researchers in the social sciences, humanities, health and biological sciences who study the older population of Canada and other countries; informs policy debates relevant to aging through the publication of the highest quality research; seeks to improve the quality of life for Canada"s older population and for older populations in other parts of the world through the publication of research that focuses on the broad range of relevant issues from income security to family relationships to service delivery and best practices.