Helping patients understand multi-cancer early detection tests: a scoping review.

Personalized medicine Pub Date : 2024-01-01 Epub Date: 2024-01-25 DOI:10.2217/pme-2023-0090
Martha Paige Greene, Jason L Vassy
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Abstract

Multi-cancer early detection tests are emerging as a revolutionary technology for the early detection of dozens of cancers from a single blood sample, including cancers without proven screening methods. However, they also come with challenges, including false-positive and false-negative results. To help patients make informed decisions, patient education materials are crucial. A review of available materials reveals that, while some materials provide understandable and actionable information, most lack a balanced presentation of the current benefits and risks of multi-cancer early detection testing. The dynamic nature of this field necessitates continuous updates to educational materials, incorporating current evidence and uncertainties.

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帮助患者了解多种癌症早期检测试验:范围界定综述。
多种癌症早期检测试验正在成为一种革命性的技术,可以从一份血液样本中早期检测出数十种癌症,包括没有成熟筛查方法的癌症。然而,它们也面临着挑战,包括假阳性和假阴性结果。为了帮助患者做出明智的决定,患者教育材料至关重要。对现有材料的审查显示,虽然有些材料提供了可理解和可操作的信息,但大多数材料缺乏对目前多种癌症早期检测的益处和风险的平衡介绍。该领域的动态性质要求不断更新教育材料,将当前的证据和不确定因素纳入其中。
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