Xinping Fan, Xueyan Jie, Fan Zou, Dan Wang, Hongju Da, Hongxin Li, Hongyan Zhao, Jin He, Jianghao Liu, Yiyi Lu, Yun Liu
{"title":"Association between outdoor air pollutants and risk of acute exacerbation of chronic obstructive pulmonary disease in Xi’an, China","authors":"Xinping Fan, Xueyan Jie, Fan Zou, Dan Wang, Hongju Da, Hongxin Li, Hongyan Zhao, Jin He, Jianghao Liu, Yiyi Lu, Yun Liu","doi":"10.1007/s11869-024-01513-6","DOIUrl":null,"url":null,"abstract":"<div><p>Attention has been paid to the association between outdoor air pollutants and acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Xi’an has special basin topography and meteorological conditions as well as developed industries. All these make the outdoor air pollution in Xi 'an serious. Thus, we wish to assess the association between outdoor air pollutants and AECOPD in Xi’an, China. Daily AECOPD inpatient and outpatient visits in 2018 were collected from the eight first-class large general hospitals at grade 3. Data on pollutants and weather conditions in Xi 'an from January 1 to December 31, 2018 were accessed from Xi 'an Environmental Protection Bureau and Xi 'an Meteorological Bureau. Spearman rank correlation, linear regression, and generalized additive models were used for data analysis. Outdoor air pollutants (PM10, PM2.5, SO<sub>2</sub>, NO<sub>2</sub>, and CO) increase the risk of AECOPD. The impact of air pollutants on AECOPD patients has a hysteresis effect. PM10, PM2.5, CO, and NO<sub>2</sub> are associated with acute exacerbation in female COPD patients. PM10, PM2.5, CO, SO<sub>2</sub>, and NO<sub>2</sub> are associated with acute exacerbation in old COPD patients (70 < age ≤ 80 years old). CO is associated with acute exacerbation in COPD Patients with eosinophils absolute count ≥ 300/μL. PM10 is associated with acute exacerbation in COPD patients with eosinophils absolute count < 100/μL. Exposure to PM10, PM2.5, SO<sub>2</sub>, NO<sub>2</sub>, and CO is positively associated significantly with hospital visits for AECOPD in Xi’an. Various air pollutants have different associations with different types of AECOPD patients. The relationship between O<sub>3</sub> and AECOPD still needs to be further explored.</p></div>","PeriodicalId":49109,"journal":{"name":"Air Quality Atmosphere and Health","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Air Quality Atmosphere and Health","FirstCategoryId":"93","ListUrlMain":"https://link.springer.com/article/10.1007/s11869-024-01513-6","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Attention has been paid to the association between outdoor air pollutants and acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Xi’an has special basin topography and meteorological conditions as well as developed industries. All these make the outdoor air pollution in Xi 'an serious. Thus, we wish to assess the association between outdoor air pollutants and AECOPD in Xi’an, China. Daily AECOPD inpatient and outpatient visits in 2018 were collected from the eight first-class large general hospitals at grade 3. Data on pollutants and weather conditions in Xi 'an from January 1 to December 31, 2018 were accessed from Xi 'an Environmental Protection Bureau and Xi 'an Meteorological Bureau. Spearman rank correlation, linear regression, and generalized additive models were used for data analysis. Outdoor air pollutants (PM10, PM2.5, SO2, NO2, and CO) increase the risk of AECOPD. The impact of air pollutants on AECOPD patients has a hysteresis effect. PM10, PM2.5, CO, and NO2 are associated with acute exacerbation in female COPD patients. PM10, PM2.5, CO, SO2, and NO2 are associated with acute exacerbation in old COPD patients (70 < age ≤ 80 years old). CO is associated with acute exacerbation in COPD Patients with eosinophils absolute count ≥ 300/μL. PM10 is associated with acute exacerbation in COPD patients with eosinophils absolute count < 100/μL. Exposure to PM10, PM2.5, SO2, NO2, and CO is positively associated significantly with hospital visits for AECOPD in Xi’an. Various air pollutants have different associations with different types of AECOPD patients. The relationship between O3 and AECOPD still needs to be further explored.
期刊介绍:
Air Quality, Atmosphere, and Health is a multidisciplinary journal which, by its very name, illustrates the broad range of work it publishes and which focuses on atmospheric consequences of human activities and their implications for human and ecological health.
It offers research papers, critical literature reviews and commentaries, as well as special issues devoted to topical subjects or themes.
International in scope, the journal presents papers that inform and stimulate a global readership, as the topic addressed are global in their import. Consequently, we do not encourage submission of papers involving local data that relate to local problems. Unless they demonstrate wide applicability, these are better submitted to national or regional journals.
Air Quality, Atmosphere & Health addresses such topics as acid precipitation; airborne particulate matter; air quality monitoring and management; exposure assessment; risk assessment; indoor air quality; atmospheric chemistry; atmospheric modeling and prediction; air pollution climatology; climate change and air quality; air pollution measurement; atmospheric impact assessment; forest-fire emissions; atmospheric science; greenhouse gases; health and ecological effects; clean air technology; regional and global change and satellite measurements.
This journal benefits a diverse audience of researchers, public health officials and policy makers addressing problems that call for solutions based in evidence from atmospheric and exposure assessment scientists, epidemiologists, and risk assessors. Publication in the journal affords the opportunity to reach beyond defined disciplinary niches to this broader readership.