Exploring the efficacy of FAPI PET/CT in the diagnosis and treatment management of colorectal cancer: a comprehensive literature review and initial experience
{"title":"Exploring the efficacy of FAPI PET/CT in the diagnosis and treatment management of colorectal cancer: a comprehensive literature review and initial experience","authors":"","doi":"10.1007/s40336-023-00609-w","DOIUrl":null,"url":null,"abstract":"<h3>Abstract</h3> <p>FAPI PET/CT, an innovative medical imaging technique, has emerged as a promising method to target fibroblast activation protein (FAP). This novel approach offers numerous benefits, such as increased tumor absorption and reduced background noise. As a result, FAPI PET/CT images demonstrate a favorable ratio of tumor signal to background, allowing for precise tumor staging, characterization, and detection. Given the heightened expression of FAP in colorectal cancer (CRC), FAPI PET/CT has the potential to revolutionize CRC staging, restaging, and monitoring, as well as enhance treatment management and improve patient prognosis. This comprehensive review aims to provide a detailed overview of the current applications of FAPI PET/CT in CRC, while also proposing future research directions, specifically in comparison to the standard FDG PET imaging modality.</p>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"55 1","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Translational Imaging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s40336-023-00609-w","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
FAPI PET/CT, an innovative medical imaging technique, has emerged as a promising method to target fibroblast activation protein (FAP). This novel approach offers numerous benefits, such as increased tumor absorption and reduced background noise. As a result, FAPI PET/CT images demonstrate a favorable ratio of tumor signal to background, allowing for precise tumor staging, characterization, and detection. Given the heightened expression of FAP in colorectal cancer (CRC), FAPI PET/CT has the potential to revolutionize CRC staging, restaging, and monitoring, as well as enhance treatment management and improve patient prognosis. This comprehensive review aims to provide a detailed overview of the current applications of FAPI PET/CT in CRC, while also proposing future research directions, specifically in comparison to the standard FDG PET imaging modality.
期刊介绍：
Clinical and Translational Imaging is an international journal that publishes timely, up-to-date summaries on clinical practice and translational research and clinical applications of approved and experimental radiopharmaceuticals for diagnostic and therapeutic purposes. Coverage includes such topics as advanced preclinical evidence in the fields of physics, dosimetry, radiation biology and radiopharmacy with relevance to applications in human subjects. The journal benefits a readership of nuclear medicine practitioners and allied professionals involved in molecular imaging and therapy.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
