The Dairy and Cancer Controversy: Milking the Evidence.

IF 4.7 2区 医学 Q1 ONCOLOGY Current Oncology Reports Pub Date : 2024-03-01 Epub Date: 2024-01-30 DOI:10.1007/s11912-024-01496-8
Taylor E Scialo, Crystal M Pace, Donald I Abrams
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Abstract

Purpose of review: Cancer risk reduction remains a significant concern for both individuals with a cancer diagnosis and those aiming to prevent it. Dairy products, a source of beneficial dietary nutrients, have sparked controversy regarding their impact on cancer risk.

Recent findings: Evidence indicates that dairy consumption, particularly milk, can decrease colorectal cancer risk. However, cow's milk, a key dairy product, exposes individuals to growth hormones, notably insulin-like growth factor-1, potentially elevating cancer risk. Extensive research supports the link between dairy intake and heightened prostate cancer risk. Nonetheless, investigations into dairy's association with breast, ovarian, and other cancers yield mixed results. The overall data on dairy and cancer remains inconclusive. Available data suggests that a diet emphasizing fiber-rich foods such as whole grains, fruits, and vegetables, while restricting milk and dairy intake-similar to the Mediterranean dietary pattern-might mitigate cancer incidence. However, further research is crucial to elucidate the precise role of dairy products in overall cancer risk.

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乳制品与癌症之争:挤出证据。
审查目的:降低癌症风险仍然是癌症患者和旨在预防癌症的人们所关心的重要问题。乳制品是有益膳食营养素的来源之一,但其对癌症风险的影响却引发了争议:有证据表明,食用乳制品,尤其是牛奶,可以降低结直肠癌风险。然而,牛奶作为一种主要的乳制品,会使人接触到生长激素,特别是胰岛素样生长因子-1,从而有可能增加患癌风险。大量研究支持乳制品摄入量与前列腺癌风险增加之间的联系。然而,对乳制品与乳腺癌、卵巢癌和其他癌症的关系的调查结果显示好坏参半。有关乳制品与癌症的总体数据仍无定论。现有数据表明,强调全谷物、水果和蔬菜等富含纤维的食物,同时限制牛奶和乳制品的摄入量--类似于地中海饮食模式--可能会降低癌症发病率。然而,进一步的研究对于阐明乳制品在总体癌症风险中的确切作用至关重要。
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来源期刊
CiteScore
8.50
自引率
0.00%
发文量
187
审稿时长
6-12 weeks
期刊介绍: This journal aims to review the most important, recently published clinical findings in the field of oncology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those affected by cancer. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as cancer prevention, leukemia, melanoma, neuro-oncology, and palliative medicine. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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