A Meta-Analysis for Postoperative Alternations of Aortic Coarctation.

IF 0.7 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Heart Surgery Forum Pub Date : 2024-01-21 DOI:10.59958/hsf.7001

Yu Bao, Zhao Wang, Sibi Shan, Xiang Wang, Yuan Gong

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Abstract

Objective: To investigate postoperative vascular changes of patients with coarctation of the aorta (CoA).

Methods: Literature review of updated articles was performed in June 2023 through the following databases: PubMed, Web of Science, EMBASE, Crohrane Library, CNKI and Wanfang database. All the case-control studies regarding the postoperative changes of vascular structure and function in patients with CoA were analyzed.

Results: A total of 596 articles from the above databases were initially identified, with 10 articles being selected for meta-analysis. The analysis showed that weighted mean difference (WMD) of carotid intima-media thickness (cIMT) was 0.07 (95% CI = 0.01~0.13, p < 0.01) and WMD of flow mediated dilation (FMD) was -4.36 (95% CI = -7.49~-1.24, p < 0.01), respectively. The postoperative cIMT of CoA patients was higher than that of the control group, but the postoperative FMD was lower than that of the control group.

Conclusions: The operation on CoA patients ameliorates anatomical deformity in the vascular structures. However, intima-media thickening and endothelial malfunction remain as the key postoperative issues.

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主动脉粥样硬化术后变化的 Meta 分析。

目的研究主动脉共通症（CoA）患者术后的血管变化：通过以下数据库对 2023 年 6 月更新的文章进行文献综述：PubMed、Web of Science、EMBASE、Crohrane Library、CNKI 和万方数据库。分析了所有关于 CoA 患者术后血管结构和功能变化的病例对照研究：从上述数据库中初步筛选出 596 篇文章，其中 10 篇文章进行了荟萃分析。分析结果显示，颈动脉内膜厚度（cIMT）的加权平均差（WMD）为0.07（95% CI = 0.01~0.13，P < 0.01），血流介导扩张（FMD）的加权平均差（WMD）为-4.36（95% CI = -7.49~-1.24，P < 0.01）。CoA患者术后cIMT高于对照组，但术后FMD低于对照组：结论：CoA 患者的手术可改善血管结构的解剖畸形。结论：CoA 患者的手术可改善血管结构的解剖畸形，但内膜增厚和内皮功能障碍仍是术后的关键问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Heart Surgery Forum 医学-外科

CiteScore

1.20

自引率

16.70%

发文量

130

审稿时长

6-12 weeks

期刊介绍： The Heart Surgery Forum® is an international peer-reviewed, open access journal seeking original investigative and clinical work on any subject germane to the science or practice of modern cardiac care. The HSF publishes original scientific reports, collective reviews, case reports, editorials, and letters to the editor. New manuscripts are reviewed by reviewers for originality, content, relevancy and adherence to scientific principles in a double-blind process. The HSF features a streamlined submission and peer review process with an anticipated completion time of 30 to 60 days from the date of receipt of the original manuscript. Authors are encouraged to submit full color images and video that will be included in the web version of the journal at no charge.