Clinical utility of and correlation between Sniffin' Sticks and TIB smell identification test (TIBSIT) among Hong Kong Chinese with or without chronic rhinosinusitis

IF 3.3 Q2 ALLERGY Frontiers in allergy Pub Date : 2024-01-24 DOI:10.3389/falgy.2024.1292342
H. W. Mak, Shi Yeung Ho, J. C. Wong, V. Chiang, Elaine Lee, Jackie S. H. Yim, Birgitta Y. H. Wong, Philip H Li
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Abstract

Olfactory dysfunction (OD) is common among patients with chronic rhinosinusitis (CRS). Validated and culturally specific tests, such as the “Sniffin’ Sticks” test (SST) and the TIB Smell Identification Test (TIBSIT), are crucial for the diagnosis and monitoring of OD. However, they have not been utilised in Hong Kong Chinese and their correlations are unknown.Twelve CRS patients and twenty healthy volunteers were prospectively recruited from a joint allergy-otorhinolaryngology clinic in Hong Kong and performed both SST and TIBSIT. Demographics, baseline characteristics and all test results were compared and analysed.Patients with CRS demonstrated significantly lower test scores than healthy controls (all p < 0.001). Significant and strong correlations were observed between all composite and subtest scores, particularly between the composite SST and TIBSIT scores (ρ = 0.789, p < 0.001). Multivariate analysis demonstrated that the presence of CRS and increasing age were significantly associated with OD.Both SST and TIBSIT are useful olfactory tests and are strongly correlated among Hong Kong Chinese. We advocate that either test can be used for measuring OD among CRS patients.
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在患有或未患有慢性鼻炎的香港华人中,嗅探棒与TIB气味鉴定测试(TIBSIT)的临床实用性及其相关性
嗅觉功能障碍(OD)在慢性鼻炎(CRS)患者中很常见。经过验证且具有文化特异性的测试,如 "嗅棒 "测试(SST)和TIB气味识别测试(TIBSIT),对于诊断和监测嗅觉障碍至关重要。我们从香港一家过敏-耳鼻喉科联合诊所招募了 12 名 CRS 患者和 20 名健康志愿者,对他们进行了 SST 和 TIBSIT 测试。对人口统计学、基线特征和所有测试结果进行了比较和分析。CRS 患者的测试得分明显低于健康对照组(所有 P < 0.001)。在所有综合和分项测试得分之间,尤其是在 SST 和 TIBSIT 综合得分之间,观察到了显著的强相关性(ρ = 0.789,p < 0.001)。多变量分析表明,CRS 的存在和年龄的增加与 OD 显著相关。我们认为这两种测试均可用于测量 CRS 患者的 OD。
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