Metastatic Pancreatic Cancer: Where Are We?

IF 4.7 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-01-18 DOI:10.3389/or.2023.11364
Abraham Hernández-Blanquisett, Valeria Quintero-Carreño, M. C. Martínez-Ávila, María Porto, María Carolina Manzur-Barbur, Emiro Buendía
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Abstract

Pancreatic cancer is one of the most lethal neoplasms worldwide; it is aggressive in nature and has a poor prognosis. The overall survival rate for pancreatic cancer is low. Most patients present non-specific symptoms in the advanced stages, which generally leads to late diagnosis, at which point there is no option for curative surgery. The treatment of metastatic pancreatic cancer includes systemic therapy, in some cases radiotherapy, and more recently, molecular targeted therapies, which can positively impact cancer control and improve quality of life. This review provides an overview of the molecular landscape of pancreatic cancer based on the most recent literature, as well as current treatment options for patients with metastatic pancreatic cancer.
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转移性胰腺癌:我们在哪里?
胰腺癌是全球致死率最高的肿瘤之一,具有侵袭性,预后较差。胰腺癌的总生存率很低。大多数患者在晚期会出现非特异性症状,这通常会导致晚期诊断,此时已无法选择根治性手术。转移性胰腺癌的治疗包括全身治疗,在某些情况下也包括放射治疗,以及最近出现的分子靶向疗法,这些疗法可对癌症控制和改善生活质量产生积极影响。本综述根据最新文献概述了胰腺癌的分子状况,以及转移性胰腺癌患者目前的治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
期刊介绍: ACS Applied Electronic Materials is an interdisciplinary journal publishing original research covering all aspects of electronic materials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials science, engineering, optics, physics, and chemistry into important applications of electronic materials. Sample research topics that span the journal's scope are inorganic, organic, ionic and polymeric materials with properties that include conducting, semiconducting, superconducting, insulating, dielectric, magnetic, optoelectronic, piezoelectric, ferroelectric and thermoelectric. Indexed/​Abstracted: Web of Science SCIE Scopus CAS INSPEC Portico
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